Evidence map›Paper›PMID 30154161›Full record

Trial reportProceedings of the National Academy of Sciences of the United States of America2018

Neurobehavioral correlates of obesity are largely heritable.

Uku Vainik, Travis E Baker, Mahsa Dadar, Yashar Zeighami, Andréanne Michaud, Yu Zhang, José C García Alanis, Bratislav Misic, D Louis Collins, Alain Dagher

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 119 citations in OpenAlex.

  1. Pooled it
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  13. Genetic contributions to brain criticality and its relationship with human cognitive functions.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  17. Body mass index-dependent shifts along large-scale gradients in human cortical organization explain dietary regulatory success.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 4 countries.

Uku VainikMontreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.
Travis E BakerMontreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.
Mahsa DadarMontreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.
Yashar ZeighamiMontreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.ORCID 0000-0002-0583-5811
Andréanne MichaudMontreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.
Yu ZhangMontreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.
José C García AlanisMontreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.ORCID 0000-0003-3459-222X
Bratislav MisicMontreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.
D Louis CollinsMontreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.
Alain DagherMontreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada; alain.dagher@mcgill.ca.
Montreal Neurological Institute and Hospital · CARutgers, The State University of New Jersey · US

Funding

CIHR
6 · The paper itself

Abstract

Recent molecular genetic studies have shown that the majority of genes associated with obesity are expressed in the central nervous system. Obesity has also been associated with neurobehavioral factors such as brain morphology, cognitive performance, and personality. Here, we tested whether these neurobehavioral factors were associated with the heritable variance in obesity measured by body mass index (BMI) in the Human Connectome Project (

Indexed as

Body Mass IndexBrainCognitionFeeding BehaviorObesityFemaleHumansMalebody mass indexbrain morphologycognitioncortical thicknesstwins

Identifiers

PMID30154161
PMCPMC6140494
OpenAlexW2952051960

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.