Evidence map›Paper›PMID 30153910›Full record

ArticleAnnals of epidemiology2018

Air pollution exposure during pregnancy: maternal asthma and neonatal respiratory outcomes.

Indulaxmi Seeni, Sandie Ha, Carrie Nobles, Danping Liu, Seth Sherman, Pauline Mendola

Abstract read
In one paragraph

Article in Annals of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. The Developmental Origins of Asthma and COPD.Annual review of physiology · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Air pollution and pregnancy.Seminars in perinatology · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Indulaxmi SeeniEunice Kennedy Shriver National Institute of Child Health and Human Development, Division of Intramural Population Health Research, Bethesda, MD.
Sandie HaEunice Kennedy Shriver National Institute of Child Health and Human Development, Division of Intramural Population Health Research, Bethesda, MD; University of California, Merced, Social Sciences and Management Building, Merced, CA.
Carrie NoblesEunice Kennedy Shriver National Institute of Child Health and Human Development, Division of Intramural Population Health Research, Bethesda, MD.
Danping LiuEunice Kennedy Shriver National Institute of Child Health and Human Development, Division of Intramural Population Health Research, Bethesda, MD; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Biostatistics Branch, Rockville, MD.
Seth ShermanThe Emmes Corporation, Rockville, MD.
Pauline MendolaEunice Kennedy Shriver National Institute of Child Health and Human Development, Division of Intramural Population Health Research, Bethesda, MD. Electronic address: pauline.mendola@nih.gov.
Eunice Kennedy Shriver National Institute of Child Health and Human Development · USEmmes (United States) · USNational Cancer Institute · USUniversity of California, Merced · US

Funding

Air Quality and Reproductive HealthZIAHD008923 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI MENDOLA, PAULINE · 2012 to 2020
$3.2M
Intramural NIH HHS Z99 HD999999Intramural NIH HHS ZIA HD008923NICHD NIH HHS HHSN275200800002CNICHD NIH HHS HHSN275200800002I
6 · The paper itself

Abstract

purposeMaternal asthma increases adverse neonatal respiratory outcomes, and pollution may further increase risk. Air quality in relation to neonatal respiratory health has not been studied.

methodsTransient tachypnea of the newborn (TTN), asphyxia, and respiratory distress syndrome (RDS) were identified using medical records among 223,375 singletons from the Consortium on Safe Labor (2002-2008). Community Multiscale Air Quality models estimated pollutant exposures. Multipollutant Poisson regression models calculated adjusted relative risks of outcomes for interquartile range increases in average exposure. Maternal asthma and preterm delivery were evaluated as effect modifiers.

resultsTTN risk increased after particulate matter (PM) less than or equal to 10-micron exposure during preconception and trimester one (9-10%), and whole-pregnancy exposure to PM less than or equal to 2.5 microns (PM

conclusionsSeveral pollutants appear to increase neonatal respiratory outcome risks.

Indexed as

Air PollutantsAir PollutionAsphyxiaAsphyxia NeonatorumAsthmaCarbon MonoxideEnvironmental ExposureFemaleHumansInfant, NewbornMaternal ExposureNitrogen OxidesOzoneParticulate MatterPregnancySulfur DioxideAir PollutantsCarbon MonoxideNitrogen OxidesOzoneParticulate MatterSulfur DioxideAsphyxiaCriteria air pollutantsMaternal asthmaRDSTTN

Identifiers

PMID30153910
PMCPMC6232679
OpenAlexW2807925508

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.