Evidence map›Paper›PMID 30153806›Full record

ArticleEnvironmental health and preventive medicine2018

Association of airborne particles, protein, and endotoxin with emergency department visits for asthma in Kyoto, Japan.

Mohammad Shahriar Khan, Souleymane Coulibaly, Takahiro Matsumoto, Yoshitaka Yano, Makoto Miura, Yukio Nagasaka, Masayuki Shima, Nobuyuki Yamagishi, Keiji Wakabayashi, Tetsushi Watanabe

Open access · goldAbstract read
In one paragraph

Article in Environmental health and preventive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

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  4. Indoor endotoxin, proximity to a major roadway, and severe asthma exacerbations among children in Puerto Rico.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Mohammad Shahriar KhanDepartment of Public Health, Kyoto Pharmaceutical University, 1 Misasagi-Shichonocho, Yamashinaku, Kyoto, 607-8412, Japan.
Souleymane CoulibalyDepartment of Public Health, Kyoto Pharmaceutical University, 1 Misasagi-Shichonocho, Yamashinaku, Kyoto, 607-8412, Japan.
Takahiro MatsumotoDepartment of Public Health, Kyoto Pharmaceutical University, 1 Misasagi-Shichonocho, Yamashinaku, Kyoto, 607-8412, Japan.
Yoshitaka YanoEducation and Research Center for Clinical Pharmacy, Kyoto Pharmaceutical University, 5 Misasagi-Nakauchcho, Yamashinaku, Kyoto, 607-8414, Japan.
Makoto MiuraRakuwakai Otowa Hospital, 2 Otowachinji-cho, Yamashinaku, Kyoto, 607-8062, Japan.
Yukio NagasakaRakuwakai Otowa Hospital, 2 Otowachinji-cho, Yamashinaku, Kyoto, 607-8062, Japan.
Masayuki ShimaDepartment of Public Health, Hyogo College of Medicine, 1-1 Mukogawacho, Nishinomiya, Hyogo, 663-8501, Japan.
Nobuyuki YamagishiFaculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotogecho, Hirakata, Osaka, 573-0101, Japan.
Keiji WakabayashiDepartment of Public Health, Kyoto Pharmaceutical University, 1 Misasagi-Shichonocho, Yamashinaku, Kyoto, 607-8412, Japan.
Tetsushi WatanabeDepartment of Public Health, Kyoto Pharmaceutical University, 1 Misasagi-Shichonocho, Yamashinaku, Kyoto, 607-8412, Japan. watanabe@mb.kyoto-phu.ac.jp.
Kyoto Pharmaceutical University · JPRakuwakai Otowa Hospital · JPHyogo Medical University · JPSetsunan University · JP

Funding

JSPS JSPS KAKENHI grant number JP17k08396the Japanese Ministry of the Environment Environment Research and Technology Development Fund (5-1453)
6 · The paper itself

Abstract

backgroundThe health effects of biological aerosols on the respiratory system are unclear. The purpose of this study was to clarify the association of airborne particle, protein, and endotoxin with emergency department visits for asthma in Kyoto City, Japan.

methodsWe collected data on emergency department visits at a hospital in Kyoto from September 2014 to May 2016. Fine (aerodynamic diameter ≤ 2.5 μm) and coarse (≥ 2.5 μm) particles were collected in Kyoto, and protein and endotoxin levels were analyzed. The association of the levels of particles, protein, endotoxin, and meteorological factors (temperature, relative humidity, wind speed, and air pressure) with emergency department visits for asthma was estimated.

resultsThere were 1 to 15 emergency department visits for asthma per week, and the numbers of visits increased in the autumn and spring, namely many weeks in September, October, and April. Weekly concentration of protein in fine particles was markedly higher than that in coarse particles, and protein concentration in fine particles was high in spring months. Weekly endotoxin concentrations in fine and coarse particles were high in autumn months, including September 2014 and 2015. Even after adjusting for meteorological factors, the concentrations of coarse particles and endotoxin in both particles were significant factors on emergency department visits for asthma.

conclusionsOur results suggest that atmospheric coarse particles and endotoxin are significantly associated with an increased risk of asthma exacerbation.

Indexed as

AdolescentAdultAgedAir PollutantsAsthmaChildEmergency Service, HospitalEndotoxinsFemaleHumansJapanMaleMiddle AgedParticle SizeParticulate MatterProteinsAir PollutantsEndotoxinsParticulate MatterProteinsAir pollutionBioaerosolsCoarse particleLipopolysaccharidePM2.5

Identifiers

PMID30153806
PMCPMC6114267
OpenAlexW2889467426

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.