Evidence map›Paper›PMID 30153736›Full record

ArticleBiointerphases2018

Analysis of the Myc-induced pancreatic

Blake M Bluestein, Fionnuala Morrish, Daniel J Graham, Li Huang, David Hockenbery, Lara J Gamble

Abstract read
In one paragraph

Article in Biointerphases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Blake M BluesteinDepartment of Bioengineering, University of Washington, Seattle, Washington 98195.
Fionnuala MorrishFred Hutchinson Cancer Research Center, Seattle, Washington 98109.
Daniel J GrahamDepartment of Bioengineering, University of Washington, Seattle, Washington 98195.
Li HuangFred Hutchinson Cancer Research Center, Seattle, Washington 98109.
David HockenberyFred Hutchinson Cancer Research Center, Seattle, Washington 98109.
Lara J GambleDepartment of Bioengineering, University of Washington, Seattle, Washington 98195.
University of Washington · USFred Hutch Cancer Center · US

Funding

Surface Analysis Facility for Biomedical ProblemsP41EB002027 · NIBIB · UNIVERSITY OF WASHINGTON · PI CASTNER, DAVID G · 2003 to 2019
$17.6M
Metabolism, protein and miRNA cross-talk in cell cycle and tumor progressionR01CA158921 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HOCKENBERY, DAVID M. · 2012 to 2016
$1.8M
NCI NIH HHS R01 CA158921NIBIB NIH HHS P41 EB002027
6 · The paper itself

Abstract

Solid tumors are a structurally complex system, composed of many different cell types. The tumor microenvironment includes nonmalignant cell types that participate in complex interactions with tumor cells. The cross talk between tumor and normal cells is implicated in regulating cell growth, metastatic potential, and chemotherapeutic drug resistance. A new approach is required to interrogate and quantitatively characterize cell to cell interactions in this complex environment. Here, the authors have applied time-of-flight secondary ion mass spectrometry (ToF-SIMS) to analyze Myc-induced pancreatic

Indexed as

Tumor MicroenvironmentAdenoma, Islet CellAmino AcidsAnimalsDisease Models, AnimalImage Processing, Computer-AssistedLipidsMiceNeuroendocrine TumorsNucleotidesPancreatic NeoplasmsProto-Oncogene Proteins c-mycSpectrometry, Mass, Secondary IonAmino AcidsLipidsMyc protein, mouseNucleotidesProto-Oncogene Proteins c-myc

Identifiers

PMID30153736
PMCPMC6113053
OpenAlexW2889450654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.