Observational studyPloS one2018
The association between 25(OH)D levels, frailty status and obesity indices in older adults.
Observational study in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Low Vitamin D Levels and Frailty Status in Older Adults: A Systematic Review and Meta-Analysis.Nutrients · 2020Pooled it
- Independent Associations of Vitamin D Levels with Visceral Fat and Metabolic Age in Adults: A Retrospective Cross-Sectional Study.Metabolites · 2026Article
- Vitamin D Deficiency, Obesity, and Metabolic Parameters in Chilean Older Adults.Journal of personalized medicine · 2026Article
- Association between neutrophil to high-density lipoprotein cholesterol ratio and hearing loss: a cross-sectional study from NHANES.Journal of health, population, and nutrition · 2025Article
- Serum vitamin D concentration and anthropometric indicators of adiposity in adults without or with low dose statin users: a cross-sectional study.Journal of health, population, and nutrition · 2024Article
- Scale-based screening and assessment of age-related frailty.Frontiers in public health · 2024Review
- Folate, vitamin B12 and vitamin D status in healthy and active home-dwelling people over 70 years.BMC geriatrics · 2023Article
- The Prevalence and Determinants of Vitamin D Status among Older Adults: Data from a Longitudinal Aging Study.International journal of preventive medicine · 2023Article
- Is Abdominal Obesity a Risk Factor for the Incidence of Vitamin D Insufficiency and Deficiency in Older Adults? Evidence from the ELSA Study.Nutrients · 2022Article
- Association between anthropometric markers of adiposity, adipokines and vitamin D levels.Scientific reports · 2022Article
- No Association between Vitamin D and Weight Gain: A Prospective, Population-Based Study.Nutrients · 2022Article
- Prevalence of Micronutrient Deficiencies and Relationship with Clinical and Patient-Related Outcomes in Pulmonary Hypertension Types I and IV.Nutrients · 2021Observational
- Anthropometric Indices and Age at Natural Menopause: A 15-Year Follow-up Population-Based Study.International journal of endocrinology and metabolism · 2021Article
- Association of serum 25-hydroxy vitamin D with obesity-related indices in Chinese adults: A cross-sectional study.Food science & nutrition · 2021Article
- Serum 25OHD3 of Obese Mice Is Affected by Liver Injury and Correlates with Testosterone Levels and Sperm Motility.Obesity facts · 2021Article
- Pinpointing a Role for Vitamin D in Frailty: A Time for Animal Models?Advances in geriatric medicine and research · 2021Article
- Associations of vitamin D with novel and traditional anthropometric indices according to age and sex: a cross-sectional study in central southern China.Eating and weight disorders : EWD · 2020Article
- Article
- Plasma 25-hydroxyvitamin D level and the risk of frailty among Chinese community-based oldest-old: evidence from the CLHLS study.BMC geriatrics · 2020Article
- Relationship Between Modified Body Adiposity Index and A Body Shape Index with Biochemical Parameters in Bariatric Surgery Candidates.Obesity surgery · 2020Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVitamin D deficiency is common in older adults and has been linked with frailty and obesity, but it remains to be studied whether frail obese older adults are at higher risk of vitamin D deficiency. Therefore, the aim of this study is to explore the association between frailty, obesity indices and serum 25(OH)D concentrations.
methods1447 individuals with 65 years or older, participating in a cross-sectional study (Nutrition UP 65) were included. Frailty, according to Fried et al., body mass index (BMI), waist circumference (WC), body roundness index (BRI) and body shape index (ABSI) were evaluated. A stepwise multinomial logistic regression was carried out to quantify the association between 25(OH)D quartiles and independent variables.
resultsMedian 25(OH)D levels were lower in individuals presenting both frailty and obesity (p<0.001). In the multivariate analysis, pre-frailty (OR: 2.65; 95% CI: 1.63-4.33) and frailty (OR: 3.77; 95% CI: 2.08-6.83) were associated with increased odds of lower 25(OH)D serum levels (first quartile). Regarding obesity indices, the highest categories of BMI (OR: 1.74; 95% CI: 1.06-2.86), WC (OR: 3.46; 95% CI: 1.95-6.15), BRI (OR: 4.35; 95% CI: 2.60-7.29) and ABSI (OR: 3.17 95% CI: 1.86-5.38) were directly associated with lower 25(OH)D serum levels (first quartile).
conclusionsA positive association between frailty or obesity and lower vitamin D levels was found. Moreover, besides BMI and WC, other indicators of body adiposity, such as BRI and ABSI, were associated with lower 25(OH)D serum concentrations.
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