Trial reportMedicine and science in sports and exercise2019
Resistance Training Volume Enhances Muscle Hypertrophy but Not Strength in Trained Men.
Trial report in Medicine and science in sports and exercise, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 15 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
112 citing papers in PubMed, 15 syntheses or guidelines pooled it.
- The Resistance Training Dose Response: Meta-Regressions Exploring the Effects of Weekly Volume and Frequency on Muscle Hypertrophy and Strength Gains.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Influence of Resistance Training Variables to Improve Muscle Mass Outcomes in Sarcopenia: A Systematic Review With Meta-Regressions.Journal of cachexia, sarcopenia and muscle · 2025Pooled it
- Acute effects of resistance exercise on skeletal muscle glycogen depletion: A systematic review and meta-analysis.Physiological reports · 2025Pooled it
- Task Specificity of Dynamic Resistance Training and Its Transferability to Non-trained Isometric Muscle Strength: A Systematic Review with Meta-analysis.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- Residual Effects of Physical Exercise After Periods of Training Cessation in Older Adults: A Systematic Review With Meta-Analysis and Meta-Regression.Scandinavian journal of medicine & science in sports · 2025Pooled it
- Pooled it
- Effects of inspiratory muscle training on lung function parameter in swimmers: a systematic review and meta-analysis.Frontiers in sports and active living · 2024Pooled it
- Effects of strength training on functional ambulation following knee replacement: a systematic review, meta-analysis, and meta-regression.Scientific reports · 2023Pooled it
- Influence of Strength Training Variables on Neuromuscular and Morphological Adaptations in Prepubertal Children: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- Is functional training an efficient approach to improve body composition in older people? A systematic review.Frontiers in physiology · 2023Pooled it
- The Acute and Chronic Effects of Implementing Velocity Loss Thresholds During Resistance Training: A Systematic Review, Meta-Analysis, and Critical Evaluation of the Literature.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- Effects of Attentional Focus on Muscular Endurance: A Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Chronic Effects of Altering Resistance Training Set Configurations Using Cluster Sets: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2021Pooled it
- A Systematic Review with Meta-Analysis of the Effect of Resistance Training on Whole-Body Muscle Growth in Healthy Adult Males.International journal of environmental research and public health · 2020Pooled it
- Maximizing Muscle Hypertrophy: A Systematic Review of Advanced Resistance Training Techniques and Methods.International journal of environmental research and public health · 2019Pooled it
- A 4-week caloric restriction with high volume resistance-training and high-protein diet does not increase fat-free mass sparing but increases strength.European journal of clinical nutrition · 2026Trial
- Physical Adaptations to High-Intensity Multimodal Training in Recreationally Active Adults: A Randomised Control Trial.European journal of sport science · 2026Trial
- Bioelectrical impedance vector analysis and phase angle in response to resistance training volume reduction in older women.European journal of clinical nutrition · 2025Trial
- The effects of high protein intakes during energy restriction on body composition, energy metabolism and physical performance in recreational athletes.European journal of clinical nutrition · 2025Trial
- Increasing set volume relative to baseline does not augment skeletal muscle adaptations when compared to maintenance of baseline training volume in recreationally trained individuals.European journal of applied physiology · 2025Trial
52 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on byResponse.2019
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to evaluate muscular adaptations between low-, moderate-, and high-volume resistance training protocols in resistance-trained men.
methodsThirty-four healthy resistance-trained men were randomly assigned to one of three experimental groups: a low-volume group performing one set per exercise per training session (n = 11), a moderate-volume group performing three sets per exercise per training session (n = 12), or a high-volume group performing five sets per exercise per training session (n = 11). Training for all routines consisted of three weekly sessions performed on nonconsecutive days for 8 wk. Muscular strength was evaluated with one repetition maximum (RM) testing for the squat and bench press. Upper-body muscle endurance was evaluated using 50% of subjects bench press 1RM performed to momentary failure. Muscle hypertrophy was evaluated using B-mode ultrasonography for the elbow flexors, elbow extensors, mid-thigh, and lateral thigh.
resultsResults showed significant preintervention to postintervention increases in strength and endurance in all groups, with no significant between-group differences. Alternatively, while all groups increased muscle size in most of the measured sites from preintervention to postintervention, significant increases favoring the higher-volume conditions were seen for the elbow flexors, mid-thigh, and lateral thigh.
conclusionsMarked increases in strength and endurance can be attained by resistance-trained individuals with just three 13-min weekly sessions over an 8-wk period, and these gains are similar to that achieved with a substantially greater time commitment. Alternatively, muscle hypertrophy follows a dose-response relationship, with increasingly greater gains achieved with higher training volumes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.