Evidence map›Paper›PMID 30152229›Full record

ArticleACS applied materials & interfaces2018

Temperature-Responsive Magnetic Nanoparticles for Enabling Affinity Separation of Extracellular Vesicles.

Ramon Jauregui, Selvi Srinivasan, Lucia N Vojtech, Hilary S Gammill, Daniel T Chiu, Florian Hladik, Patrick S Stayton, James J Lai

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Magnetic nanomaterials in analytical chemistry: toward enhanced separation and detection methodologies.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Biodistribution of therapeutic extracellular vesicles.Extracellular vesicles and circulating nucleic acids · 2023
    Review
  7. Review
  8. Exosome Processing and Characterization Approaches for Research and Technology Development.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Immune cell engineering: opportunities in lung cancer therapeutics.Drug delivery and translational research · 2020
    Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ramon Jauregui
Selvi Srinivasan
Lucia N Vojtech
Hilary S Gammill
Florian Hladik
Patrick S Stayton

Funding

UW Post-Baccalaureate Research Education Program (PREP)R25GM086304 · NIGMS · UNIVERSITY OF WASHINGTON · PI Gabriele Varani · 2011 to 2026
$5.7M
Placentomics using a novel method to isolate circulating placental derivativesR01HD089679 · NICHD · UNIVERSITY OF WASHINGTON · PI CHIU, DANIEL T, GRAVETT, MICHAEL G · 2016 to 2020
$3.1M
Extracellular vesicles in semen and genital HIV infection and immunity during heroin addiction and methadone or buprenorphine substitution therapyR01DA040386 · NIDA · UNIVERSITY OF WASHINGTON · PI HLADIK, FLORIAN · 2015 to 2019
$2.6M
Biospecimen preparation technologies to enable high throughput and highly sensitiR21CA174581 · NCI · UNIVERSITY OF WASHINGTON · PI LAI, JAMES · 2013 to 2015
$692k
Mechanisms of sexual Zika virus transmission and early immunopathogenesisR21AI129303 · NIAID · UNIVERSITY OF WASHINGTON · PI VOJTECH, LUCIA N · 2017 to 2018
$426k
The Role of Exosomes in Semen for HIV Infection in the Genital Mucosa of WomenR21AI095023 · NIAID · UNIVERSITY OF WASHINGTON · PI HLADIK, FLORIAN · 2011 to 2012
$385k
NCI NIH HHS R21 CA174581NIAID NIH HHS R21 AI095023NIAID NIH HHS R21 AI129303NICHD NIH HHS R01 HD089679NIDA NIH HHS R01 DA040386NIGMS NIH HHS R25 GM086304
6 · The paper itself

Abstract

Small magnetic nanoparticles that have surfaces decorated with stimuli-responsive polymers can be reversibly aggregated via a stimulus, such as temperature, to enable efficient and rapid biomarker separation. To fully realize the potential of these particles, the synthesis needs to be highly reproducible and scalable to large quantity. We have developed a new synthesis for temperature-responsive magnetic nanoparticles via an in situ co-precipitation process of Fe

Indexed as

Magnetic FieldsAnimalsCoated Materials, BiocompatibleExtracellular VesiclesHumansImmunoglobulin GMagnetite NanoparticlesMaleMiceSemenCoated Materials, BiocompatibleImmunoglobulin GMagnetite Nanoparticlesbiomarkersdiblock co-polymerextracellular vesiclemagnetic nanoparticlestimuli-responsive polymer

Identifiers

PMID30152229
PMCPMC6538933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.