Evidence map›Paper›PMID 30152056›Full record

ReviewBritish journal of pharmacology2019

Nitrite and nitrate chemical biology and signalling.

Anthony W DeMartino, Daniel B Kim-Shapiro, Rakesh P Patel, Mark T Gladwin

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in British journal of pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 81 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 2 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01431313 phase2completednot on this map

A Dose Escalation Study to Evaluate the Effect of Inhaled Nitrite on Cardiopulmonary Hemodynamics in Subjects With Pulmonary Hypertension

TypeinterventionalSponsorSchmidhofer, Mark, MDRan2012 to 2017Enrolled48ConditionsPulmonary Hypertension, Heart Failure, DiastolicArmsInhaled Nitrite
NCT06375694 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Oral Probiotic Effect on Dietary Nitrate to Plasma Nitrite Production

TypeinterventionalSponsorWake Forest UniversityRan2024 to 2025Enrolled20ConditionsHypertension, Cardiovascular Diseases, DiabetesArmsHerbiotics Oral + Ent Probiotic, Placebo
3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 2 syntheses or guidelines pooled it, 154 citations in OpenAlex.

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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Anthony W DeMartinoHeart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0001-5303-5758
Daniel B Kim-ShapiroDepartment of Physics, Wake Forest University, Winston-Salem, NC, USA.
Rakesh P PatelDepartment of Pathology and Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, USA.
Mark T GladwinHeart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · USUniversity of Alabama at Birmingham · USWake Forest University · US

Funding

Vascular Subphenotypes of Lung DiseaseP01HL103455 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GLADWIN, MARK T · 2011 to 2020
$26.1M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide HomeostasisR01HL098032 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Mark T Gladwin · 2009 to 2026
$12.5M
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobinR01HL125886 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Mark T Gladwin, Jesus Tejero Bravo · 2015 to 2026
$7.9M
Translational Pulmonary Vascular BiologyT32HL110849 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Sruti Shiva · 2012 to 2026
$5.0M
NHLBI NIH HHS P01 HL103455NHLBI NIH HHS R01 HL098032NHLBI NIH HHS R01 HL125886NHLBI NIH HHS T32 HL110849NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

Inorganic nitrate (NO

Indexed as

Signal TransductionAnimalsHumansHydrogen-Ion ConcentrationKineticsNitratesNitric OxideNitritesOxygenNitratesNitric OxideNitritesOxygen

Identifiers

PMID30152056
PMCPMC6295445
OpenAlexW2889070546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.