Evidence map›Paper›PMID 30152014›Full record

ArticleClinical genetics2018

A multicenter study to evaluate pulmonary function in osteogenesis imperfecta.

Allison Tam, Shan Chen, Evan Schauer, Ingo Grafe, Venkata Bandi, Jay R Shapiro, Robert D Steiner, Peter A Smith, Michael B Bober, Tracy Hart and 13 more

Abstract readMulticenter Study
In one paragraph

Article in Clinical genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Targeting TGF-β for treatment of osteogenesis imperfecta.The Journal of clinical investigation · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 11 institutions in 2 countries.

Allison TamDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.
Shan ChenDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.
Evan SchauerDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.
Ingo GrafeDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.
Venkata BandiDepartment of Medicine, Baylor College of Medicine, Houston, Texas.
Jay R ShapiroDepartment of Bone and Osteogenesis Imperfecta, Kennedy Krieger Institute, Baltimore, Maryland.
Robert D SteinerSchool of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin.
Peter A SmithShriner's Hospitals for Children, Chicago, Illinois.
Michael B BoberDivision of Medical Genetics, Alfred I du Pont Hospital for Children, Wilmington, Delaware.
Tracy HartOsteogenesis Imperfecta Foundation, Gaithersburg, Maryland.
David CuthbertsonCollege of Medicine, University of South Florida, Tampa, Florida.
Jeffrey KrischerCollege of Medicine, University of South Florida, Tampa, Florida.
Mary MullinsDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.
Peter H ByersDepartments of Medicine and Pathology, Division of Medical Genetics, University of Washington, Seattle, Western Australia.
Robert A SandhausDivision of Pulmonary Critical Care and Sleep Medicine, National Jewish Health, Denver, Colorado.
Michaela DurigovaShriner's Hospital for Children, McGill University, Montreal, Canada.
Francis H GlorieuxShriner's Hospital for Children, McGill University, Montreal, Canada.
Frank RauchShriner's Hospital for Children, McGill University, Montreal, Canada.
Vernon Reid SuttonDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.
Brendan LeeDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.
Members of the Brittle Bone Disorders Consortium
Eric T RushChildren's Mercy Hospital, University of Missouri-Kansas City, Kansas City, Missouri.
Sandesh C S NagamaniDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.ORCID 0000-0001-6818-7367
Baylor College of Medicine · USMontreal Children's Hospital · CAUniversity of South Florida · USAlfred I. duPont Hospital for Children · USChildren's Mercy Hospital · USKennedy Krieger Institute · USNational Jewish Health · USOsteogenesis Imperfecta Foundation · USShriners Hospitals for Children - Chicago · USUniversity of Washington Medical Center · USUniversity of Wisconsin–Madison · US

Funding

Project 3: 3D ImagingU54AR068069 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI Brendan Lee · 2014 to 2026
$19.3M
Project 3: Collagen post-translational modification and cross-linking in OIP01HD070394 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI LEE, BRENDAN · 2011 to 2020
$13.4M
MEDICAL GENETICS RESEARCH FELLOWSHIP PROGRAMT32GM007526 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI Brendan Lee · 1985 to 2026
$11.4M
Steps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, SAMACO, RODNEY C · 2014 to 2019
$7.8M
NIAMS NIH HHS U54 AR068069NICHD NIH HHS P01 HD070394NICHD NIH HHS U54 HD083092NIGMS NIH HHS T32 GM007526
6 · The paper itself

Abstract

Pulmonary complications are a significant cause for morbidity and mortality in osteogenesis imperfecta (OI). However, to date, there have been few studies that have systematically evaluated pulmonary function in individuals with OI. We analyzed spirometry measurements, including forced vital capacity (FVC) and forced expiratory volume in the first second (FEV

Indexed as

AdolescentAdultAgedChildFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedOsteogenesis ImperfectaRespiratory Function TestsSeverity of Illness IndexSpirometryVital CapacityYoung Adultlung diseaseosteogenesis imperfectapulmonary functionspirometry

Identifiers

PMID30152014
PMCPMC6235719
OpenAlexW2889151065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.