ArticleGlia2018
Enhanced oligodendrocyte maturation and myelination in a mouse model of Timothy syndrome.
Open access · greenAbstract read
In one paragraph
Article in Glia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Calcium channelopathies and intellectual disability: a systematic review.Orphanet journal of rare diseases · 2021Pooled it
- Intranasal stem cell treatment ameliorates neuroinflammation and myelin aberrations in fetal growth-restricted rat pups.Stem cells translational medicine · 2026Article
- Myelin dysfunction in autism spectrum disorder: insights into core symptoms and mechanisms of brain development.Molecular psychiatry · 2026Review
- Voltage-Gated and Chemogenetic Modulation of Calcium Signaling in Oligodendrocyte Development and Synaptic Integration.Journal of neurochemistry · 2025Review
- L-type calcium channels and neuropsychiatric diseases: Insights into genetic risk variant-associated genomic regulation and impact on brain development.Channels (Austin, Tex.) · 2023Review
- A single-cell trajectory atlas of striatal development.Scientific reports · 2023Article
- CACNA1C-Related Channelopathies.Handbook of experimental pharmacology · 2023Review
- Neuronal deletion of CaScientific reports · 2022Article
- DisruptedProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Modeling human neurodevelopmental diseases with brain organoids.Cell regeneration (London, England) · 2022Review
- Ion Channels as New Attractive Targets to Improve Re-Myelination Processes in the Brain.International journal of molecular sciences · 2021Review
- Patient-Derived Induced Pluripotent Stem Cells (iPSCs) and Cerebral Organoids for Drug Screening and Development in Autism Spectrum Disorder: Opportunities and Challenges.Pharmaceutics · 2021Review
- Neuron to Oligodendrocyte Precursor Cell Synapses: Protagonists in Oligodendrocyte Development and Myelination, and Targets for Therapeutics.Frontiers in neuroscience · 2021Review
- Can Enhancing Neuronal Activity Improve Myelin Repair in Multiple Sclerosis?Frontiers in cellular neuroscience · 2021Review
- Cav1.2 channelopathies causing autism: new hallmarks on Timothy syndrome.Pflugers Archiv : European journal of physiology · 2020Review
- CaCellular and molecular neurobiology · 2019Review
- Dysfunctional Cav1.2 channel in Timothy syndrome, from cell to bedside.Experimental biology and medicine (Maywood, N.J.) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Veronica T CheliHunter James Kelly Research Institute, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, The State University of New York, University at Buffalo, Buffalo, New York.
Diara A Santiago GonzálezHunter James Kelly Research Institute, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, The State University of New York, University at Buffalo, Buffalo, New York.
Norma N ZamoraHunter James Kelly Research Institute, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, The State University of New York, University at Buffalo, Buffalo, New York.
Tenzing N LamaHunter James Kelly Research Institute, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, The State University of New York, University at Buffalo, Buffalo, New York.
Vilma SpreuerHunter James Kelly Research Institute, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, The State University of New York, University at Buffalo, Buffalo, New York.
Randall L RasmussonDepartment of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, The State University of New York, University at Buffalo, Buffalo, New York.
Glenna C BettDepartment of Obstetrics and Gynecology, Jacobs School of Medicine and Biomedical Sciences, The State University of New York, University at Buffalo, Buffalo, New York.
Georgia PanagiotakosDepartment of Biochemistry and Biophysics and Kavli Institute for Fundamental Neuroscience, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, School of Medicine, University of California at San Francisco, San Francisco, California.
Pablo M PaezHunter James Kelly Research Institute, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, The State University of New York, University at Buffalo, Buffalo, New York.ORCID 0000-0001-9362-9454
New York University · USBroad Center · US
Funding
Enabling Access to Cutting-Edge Biomedical and Behavioral ScienceR25GM095459 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI DUBOCOVICH, MARGARITA L · 2012 to 2021
$4.4MModulation of Oligodendrocyte Development by Voltage-Operated Calcium ChannelsR01NS078041 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Pablo Martin Paez · 2013 to 2026
$3.8MNIGMS NIH HHS R25 GM095459NINDS NIH HHS R01 NS078041NINDS NIH HHS R01NS078041
Abstract
To study the role of L-type voltage-gated Ca
Indexed as
AnimalsAnimals, NewbornAutistic DisorderAutophagy-Related ProteinsBacterial ProteinsBasic Helix-Loop-Helix ProteinsCalciumCalcium Channels, L-TypeCell DifferentiationCells, CulturedCerebral CortexCoculture TechniquesDisease Models, AnimalGene Expression Regulation, DevelopmentalIntracellular Signaling Peptides and ProteinsLong QT SyndromeAutophagy-Related ProteinsBacterial ProteinsBasic Helix-Loop-Helix ProteinsCACNA1C protein, mouseCalciumCalcium Channels, L-TypeIntracellular Signaling Peptides and ProteinsLuminescent ProteinsMyelin ProteinsNerve Tissue ProteinsOlig1 protein, mousePotassiumRb1cc1 protein, mouseyellow fluorescent protein, BacteriaautismCav1.2myelinationoligodendrocyteTimothy syndromevoltage-gated calcium channels
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.