ArticleMolecular neurobiology2019
Astrocytic Mechanisms Involving Kynurenic Acid Control Δ
Open access · greenAbstract read
In one paragraph
Article in Molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 34% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- BrainFrontiers in immunology · 2021Pooled it
- Effects of nicotinic receptor antagonism on nicotine and THC self-administration in a model of polysubstance use.The international journal of neuropsychopharmacology · 2026Article
- The role of the kynurenine pathway in conditioned place aversion induced by synthetic cannabinoid CP-55940.Behavioral and brain functions : BBF · 2026Article
- The need to incorporate polysubstance use in neuropsychopharmacology research: Biological lessons and new opportunities.Addiction neuroscience · 2026Article
- Effects of nicotinic receptor antagonism on nicotine and THC self-administration in a model of polysubstance use.bioRxiv : the preprint server for biology · 2025Article
- Article
- Extracellular glutamate is not modulated by cannabinoid receptor activity.Scientific reports · 2024Article
- The Impacts of Adolescent Cannabinoid Exposure on Striatal Anxiety- and Depressive-Like Pathophysiology Are Prevented by the AntioxidantBiological psychiatry global open science · 2024Article
- Neuroactive Kynurenines as Pharmacological Targets: New Experimental Tools and Exciting Therapeutic Opportunities.Pharmacological reviews · 2024Review
- Astrocytic Regulation of Endocannabinoid-Dependent Synaptic Plasticity in the Dorsolateral Striatum.International journal of molecular sciences · 2024Article
- The Atypical Dopamine Transporter Inhibitor CE-158 Enhances Dopamine Neurotransmission in the Prefrontal Cortex of Male Rats: A Behavioral, Electrophysiological, and Microdialysis Study.The international journal of neuropsychopharmacology · 2023Article
- Targeting corticostriatal transmission for the treatment of cannabinoid use disorder.Trends in pharmacological sciences · 2023Review
- Role of mesolimbic cannabinoid receptor 1 in stress-driven increases in cocaine self-administration in male rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Article
- Influx of kynurenine into the brain is involved in the reduction of ethanol consumption induced by Ro 61-8048 after chronic intermittent ethanol in mice.British journal of pharmacology · 2022Article
- Alterations in rat prefrontal cortex kynurenic acid levels are involved in the enduring cognitive dysfunctions induced by tetrahydrocannabinol exposure during the adolescence.Frontiers in psychiatry · 2022Article
- Receptor mechanisms underlying the CNS effects of cannabinoids: CBAdvances in pharmacology (San Diego, Calif.) · 2022Article
- Reinstatement of synaptic plasticity in the aging brain through specific dopamine transporter inhibition.Molecular psychiatry · 2021Article
- HIV Transgenic Rats Demonstrate Impaired Sensorimotor Gating But Are Insensitive to Cannabinoid (Δ9-Tetrahydrocannabinol)-Induced Deficits.The international journal of neuropsychopharmacology · 2021Article
- Repeated exposure to JWH-018 induces adaptive changes in the mesolimbic and mesocortical dopaminergic pathways, glial cells alterations, and behavioural correlates.British journal of pharmacology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 4 institutions in 2 countries.
Maria E SecciBehavioral Neuroscience Research Branch, Intramural Research Program, Department of Health and Human Services, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd., Baltimore, MD, 21224, USA.
Paola MasciaBehavioral Neuroscience Research Branch, Intramural Research Program, Department of Health and Human Services, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd., Baltimore, MD, 21224, USA.
Claudia SaghedduDepartment of Biomedical Sciences, University of Cagliari, Monserrato, Italy.
Sarah BeggiatoMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Miriam MelisDepartment of Biomedical Sciences, University of Cagliari, Monserrato, Italy.
Andrea C BorelliDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
Maria C TomasiniDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Leigh V PanlilioBehavioral Neuroscience Research Branch, Intramural Research Program, Department of Health and Human Services, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd., Baltimore, MD, 21224, USA.
Charles W SchindlerBehavioral Neuroscience Research Branch, Intramural Research Program, Department of Health and Human Services, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd., Baltimore, MD, 21224, USA.
Gianluigi TandaMolecular Targets and Medications Discovery Branch, Intramural Research Program, Department of Health and Human Services, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA.
Sergi FerréMolecular Targets and Medications Discovery Branch, Intramural Research Program, Department of Health and Human Services, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA.
Charles W BradberryBehavioral Neuroscience Research Branch, Intramural Research Program, Department of Health and Human Services, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd., Baltimore, MD, 21224, USA.
Luca FerraroDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Marco PistisDepartment of Biomedical Sciences, University of Cagliari, Monserrato, Italy.
Steven R GoldbergBehavioral Neuroscience Research Branch, Intramural Research Program, Department of Health and Human Services, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd., Baltimore, MD, 21224, USA.
Robert SchwarczMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Zuzana JustinovaBehavioral Neuroscience Research Branch, Intramural Research Program, Department of Health and Human Services, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd., Baltimore, MD, 21224, USA. zuzana.justinova@nih.gov.ORCID http://orcid.org/0000-0001-5793-7484
National Institutes of Health · USUniversity of Cagliari · ITUniversity of Ferrara · ITUniversity of Maryland, Baltimore · US
Funding
The Effects of Kynurenine Aminotransferase Inhibition in People with SchizophreniaP50MH103222 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI SCHWARCZ, ROBERT · 2014 to 2023
$25.2MMultimodal preclinical imaging studies of decisional determinants of drug vs non-drug choiceZIADA000622 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI JEDEMA, HANK · 2017 to 2025
$21.9MControl Of Behavior By Drug InjectionsZIADA000001 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI SHAHAM, YAVIN · 2009 to 2016
$8.3MDrugs On Learned & Spontaneous Behavior Of Experimental AnimalsZIADA000003 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI SHAHAM, YAVIN · 2009 to 2017
$6.8MIntramural NIH HHS Z99 DA999999Intramural NIH HHS ZIA DA000001Intramural NIH HHS ZIA DA000622NIDA NIH HHS 1ZIADA000003 29NIDA NIH HHS 1ZIADA000622 01NIMH NIH HHS P50 MH103222Università degli Studi di Ferrara FAR GrantU.S. Public Health Service P50-MH103222
Abstract
The reinforcing effects of Δ
Indexed as
RewardAction Potentialsalpha7 Nicotinic Acetylcholine ReceptorAnimalsAstrocytesBrainCells, CulturedDronabinolGlutamic AcidKynurenic AcidMaleNucleus AccumbensPrefrontal CortexRats, Sprague-DawleyReceptor, Cannabinoid, CB1Rimonabantalpha7 Nicotinic Acetylcholine ReceptorDronabinolGlutamic AcidKynurenic AcidReceptor, Cannabinoid, CB1RimonabantRNA, MessengerRo 61-8048SulfonamidesThiazolesAstrocytesCannabinoidsGlutamateKynurenic acidRatTHC
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.