ArticleSocial psychiatry and psychiatric epidemiology2019
Excessive mortality and causes of death among patients with personality disorder with comorbid psychiatric disorders.
Article in Social psychiatry and psychiatric epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Co-occurrence of psychotic disorders and borderline personality disorder: a systematic review and meta-analysis.Psychological medicine · 2026Pooled it
- Association of circulating monocyte number and monocyte-lymphocyte ratio with cardiovascular disease in patients with bipolar disorder.BMC psychiatry · 2024Article
- The Co-occurrence of Personality Disorders and Substance Use Disorders.Current psychiatry reports · 2023Review
- Mortality in people with mental disorders in Poland: A nationwide, register-based cohort study.European psychiatry : the journal of the Association of European Psychiatrists · 2022Article
- Total and cause-specific mortality in patients with personality disorders: the association between comorbid severe mental illness and substance use disorders.Social psychiatry and psychiatric epidemiology · 2021Article
- [Disease burden of borderline personality disorder: cost of illness, somatic comorbidity and mortality].Der Nervenarzt · 2021Review
- Age Effect on Incidence, Physical, and Psychiatric Comorbidity for Sudden Cardiac Death in Schizophrenia: Effet de l'âge sur l'incidence, la comorbidité physique et psychiatrique de la mort cardiaque subite dans la schizophrénie.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2021Article
- Exploration of morbidity, suicide and all-cause mortality in a Scottish forensic cohort over 20 years.BJPsych open · 2020Article
- PTSD's risky behavior criterion: Associated risky and unhealthy behaviors and psychiatric correlates in a nationally representative sample.Journal of anxiety disorders · 2020Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
purposeExcessive mortality has been seen in patients with personality disorder (PD), but it has not been well-studied when patients also have other psychiatric comorbidities. This study investigated the mortality rates and causes of death in an Asian cohort with PD.
methodWe enrolled patients ≥ 18 years of age with PD as defined by DSM-IV criteria (N = 1172), who had been admitted to a psychiatric service center in northern Taiwan between 1985 and 2008. By linking with the national mortality database (1985-2008), cases of mortality (n = 156, 13.3%) were obtained. We calculated the standardized mortality ratios (SMRs) to estimate the mortality gap between patients with PD and the general population. Stratified analyses of mortality rates by Axis I psychiatric comorbidity and sex were performed.
resultsBorderline PD (n = 391, 33.4%) was the dominant disorder among the subjects. The SMRs for all-cause mortality of PD alone, PD comorbid with non-substance use disorder(non-SUD), and PD comorbid with SUD were 4.46 (95% CI 1.94-6.98), 7.42 (5.99-8.85), and 15.96 (11.07-20.85), respectively. Among the causes of death, the SMR for suicide was the highest (46.92, 95% CI 34.29-59.56). The SMR for suicide in PD patients with comorbid SUD was unusually high (74.23, 95% CI 33.88-114.58). Women had a significant increase in suicide with an SMR of 59.00 (95% CI 37.89-80.11). Men had significant increase in SMRs for cardiovascular disease and gastrointestinal disease.
conclusionsWe found significant synergistic effects of PD and SUD on mortality risk. A personality assessment should be mandatory in all clinical settings to prevent premature death and detect SUD early.
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