Evidence map›Paper›PMID 30151268›Full record

ArticleJournal of gastrointestinal oncology2018

Clinicopathologic features and outcomes of gastrointestinal stromal tumors arising from the esophagus and gastroesophageal junction.

Andrew M Briggler, Rondell P Graham, Gustavo F Westin, Andrew L Folpe, Dawn E Jaroszewski, Scott H Okuno, Thorvardur R Halfdanarson

Open access · hybridAbstract read
In one paragraph

Article in Journal of gastrointestinal oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  5. Article
  6. Rapidly Growing Gastrointestinal Stromal Tumor on the Esophagus.The Korean journal of helicobacter and upper gastrointestinal research · 2025
    Article
  7. Article
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Andrew M BrigglerDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Rondell P GrahamDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Gustavo F WestinDepartment of Medical Oncology, Mayo Clinic, Rochester, MN, USA.
Andrew L FolpeDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Dawn E JaroszewskiDepartment of Cardiothoracic Surgery, Mayo Clinic, Scottsdale, AZ, USA.
Scott H OkunoDepartment of Medical Oncology, Mayo Clinic, Rochester, MN, USA.
Thorvardur R HalfdanarsonDepartment of Medical Oncology, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur aim was to characterize the clinicopathological features and outcomes of gastrointestinal stromal tumors (GISTs) arising from the esophagus and gastroesophageal junction (GEJ) and describe the survival of patients treated at our institution as well as from a national hospital-based registry.

methodsTwenty-eight cases were identified using the Mayo Clinic Cancer Registry from 1997 to 2016, and 1,010 cases from the National Cancer Database (NCDB) between 2004 and 2014, with analysis of TNM staging, histopathological features, mitotic index, immunohistochemical studies, and KIT mutational analysis.

resultsAt Mayo Clinic, the tumors ranged in size from 0.3-13 cm (mean 5.40 cm). IHC results were: CD117 (

conclusionsAmong esophageal and GEJ GISTs, metastatic disease was associated with increased mitotic count and increased tumor size. Men were found to have inferior OS. The Joensuu risk criteria were validated for risk stratification of esophageal and GEJ GISTs.

Indexed as

esophagusgastroesophageal junction (GEJ)Gastrointestinal stromal tumor (GIST)sarcoma

Identifiers

PMID30151268
PMCPMC6087867
OpenAlexW2808631862

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.