Evidence map›Paper›PMID 30151244›Full record

ArticleCurrent health sciences journal

Possible role of vitamin D3 on the adipocyte/fibroblast trans-differentiation mediated by pancreas cancer

S Chirumbolo

Abstract read
In one paragraph

Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

S ChirumboloLaboratory of Physiopathology of Obesity, University Laboratory of Medical Research-Department of Medicine, University of Verona, Italy.
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In pancreatic tumors, white adipose tissue and metabolic disorders related to adipocytes, are recently reviewed as important co-factors in pancreas pathology. Cell differentiation in pancreatic cancer might involve therefore adipose tissue and factors released by adipocytes should play a fundamental role both in cancer onset and in its progression. Among these molecules, a great interest has been devoted quite recently to the hormonal role exerted by vitamin D3 in pancreatic cancer, particularly its active 1,25 dihydroxylated form. Despite the wide bulk of evidence reporting the chemopreventive role of vitamin D, the mechanism by which active vitamin D3 is able to counteract cancer progression and malignancy is yet far to be elucidated.

Indexed as

adipocytepancreas cancervitamin D3

Identifiers

PMID30151244
PMCPMC6057533
OpenAlexW2182955743

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.