Evidence map›Paper›PMID 30151235›Full record

ArticlePorcine health management2018

Initial vaccination and revaccination with Type I PRRS 94881 MLV reduces viral load and infection with porcine reproductive and respiratory syndrome virus.

Jeremy Kroll, Michael Piontkowski, Christian Kraft, Teresa Coll, Oliver Gomez-Duran

Open access · goldAbstract read
In one paragraph

Article in Porcine health management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jeremy KrollDepartment of Research and Development, Boehringer Ingelheim Animal Health Inc, 2412 South Loop Drive, Ames, IA 50010 USA.
Michael PiontkowskiBoehringer Ingelheim Animal Health, 2621 N. Belt Hwy, St Joseph, MO 64506 USA.
Christian KraftBoehringer Ingelheim Veterinary Research Center GmbH & Co. KG, Bemeroder Straβe 31, 30559 Hannover, Germany.
Teresa CollBoehringer Ingelheim Veterinary Research Center GmbH & Co. KG, Bemeroder Straβe 31, 30559 Hannover, Germany.
Oliver Gomez-Duran4Boehringer Ingelheim Vetmedica GmbH, Binger Straβe 173, 55216 Ingelheim am Rhein, Germany.
Boehringer Ingelheim (Germany) · DEBoehringer Ingelheim (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPorcine reproductive and respiratory syndrome (PRRS) causes respiratory distress in pigs, reproductive failure in breeding-age gilts and sows, and can have devastating economic consequences in domestic herds. Several PRRS vaccines are available commercially. This study compared the effectiveness of single-vaccination and revaccination schedules using the PRRS 94881 Type I modified live virus (MLV) vaccine ReproCyc® PRRS EU with no vaccination (challenge control) in protecting against a PRRS virus (PRRSV) challenge in non-pregnant gilts.

resultsData were available from 48 gilts across three groups: a challenge control group (

conclusionsBoth single-vaccination and revaccination with ReproCyc® PRRS EU were effective in reducing PRRSV viremia post-challenge. These findings have important implications for herd management as both the single-vaccination and revaccination schedules protect against PRRSV challenge, with revaccination appearing to provide better protection from viremia than single vaccination.

Indexed as

Porcine reproductive respiratory syndrome (PRRS)PRRS 94881 MLVRevaccinationViral RNA load

Identifiers

PMID30151235
PMCPMC6100718
OpenAlexW2888158018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.