Evidence map›Paper›PMID 30151230›Full record

ArticleObesity science & practice2018

Effects of consuming a high-protein diet with or without soy protein during weight loss and maintenance: a non-inferiority, randomized clinical efficacy trial.

K J Speaker, R D Sayer, J C Peters, H N Foley, Z Pan, H R Wyatt, M R Flock, R Mukherjea, J O Hill

Registry-linked trialAbstract read
In one paragraph

Article in Obesity science & practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03248804 (The Effect of Incorporating Soy Protein Foods in the Colorado Diet for Weight Loss and Maintenance.), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03248804 nacompletednot on this map

The Effect of Incorporating Soy Protein Foods in the Colorado Diet for Weight Loss and Maintenance.

TypeinterventionalSponsorUniversity of Colorado, DenverRan2015 to 2016Enrolled71ConditionsOverweight, Obesity, Weight LossArmsSoy group, Non-soy group
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Effect of different protein diets on weight loss, inflammatory markers, and cardiometabolic risk factors in obese women.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

K J SpeakerAnschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA.ORCID 0000-0001-5945-5243
R D SayerAnschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA.ORCID 0000-0002-9488-7030
J C PetersAnschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA.ORCID 0000-0003-2302-8033
H N FoleyAnschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA.
Z PanDepartment of Biostatistics and Informatics, Colorado School of Public Health University of Colorado Anschutz Medical Campus Aurora CO USA.ORCID 0000-0002-9319-2501
H R WyattAnschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA.ORCID 0000-0003-1651-4092
M R FlockClinical & Translational Science Institute University of Pittsburgh Pittsburgh PA USA.
R MukherjeaGlobal Nutrition Innovation DuPont Nutrition & Health St. Louis MO USA.ORCID 0000-0002-2656-1733
J O HillAnschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA.ORCID 0000-0003-4690-2264

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Wendy M Kohrt · 1995 to 2026
$32.6M
Obesity and Cardiovascular Disease: Opportunity for Post-Doctoral TrainingT32HL116276 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ECKEL, ROBERT H · 2014 to 2018
$1.2M
NCRR NIH HHS UL1 RR025780NHLBI NIH HHS T32 HL116276NIDDK NIH HHS P30 DK048520
6 · The paper itself

Abstract

objectiveThis 12-month randomized, non-inferiority clinical trial sought to determine the impact of consuming soy protein as part of an energy-restricted, high-protein diet on weight loss, body composition and cardiometabolic health.

methodsSeventy-one adults (58 female) with overweight or obesity (body mass index: 32.9 ± 3.6 kg m

resultsBody weight was reduced in both groups at M4 (S: -7.0% ± 5.2%, NS: -7.1% ± 5.7%) and M12 (S: 3.6% ± 5.1%, NS: -4.8% ± 7.3%). Body weight reductions (mean difference [90% confidence interval]) were not different between S and NS at either time point (M4: -0.16% [-1.4, 3.6],

conclusionThese results indicate that soy-based protein foods can be effectively incorporated into an energy-restricted, high-protein diet for improving body weight, body composition and cardiometabolic health.

Indexed as

Body compositiondietary proteinobesityweight loss

Identifiers

PMID30151230
PMCPMC6105701

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.