Evidence map›Paper›PMID 30151097›Full record

ArticleJournal of thyroid research2018

Metabolic Syndrome and Subclinical Hypothyroidism: A Type 2 Diabetes-Dependent Association.

Valmore Bermúdez, Juan Salazar, Roberto Añez, Milagros Rojas, Viviana Estrella, María Ordoñez, Maricarmen Chacín, Juan Diego Hernández, Víctor Arias, Mayela Cabrera and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thyroid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. The role of thyroid hormone in metabolism and metabolic syndrome.Therapeutic advances in endocrinology and metabolism · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Valmore BermúdezUniversidad Simón Bolívar, Facultad de Ciencias de la Salud, Barranquilla, Colombia.ORCID 0000-0003-1880-8887
Juan SalazarEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.ORCID 0000-0003-4211-528X
Roberto AñezEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.
Milagros RojasEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.
Viviana EstrellaUniversidad de Especialidades Espíritu Santo, Cantón de Samborondón, Provincia de Guayas, Ecuador.
María OrdoñezUniversidad de Especialidades Espíritu Santo, Cantón de Samborondón, Provincia de Guayas, Ecuador.
Maricarmen ChacínEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.
Juan Diego HernándezGrupo de Investigación Altos Estudios de Frontera (ALEF), Universidad Simón Bolívar, Colombia.
Víctor AriasGrupo de Investigación Altos Estudios de Frontera (ALEF), Universidad Simón Bolívar, Colombia.
Mayela CabreraLone Star College, Biology Department, Tomball, TX 77381, USA.
Clímaco Cano-PonceEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.
Joselyn RojasEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.
Universidad del Zulia · VEUniversidad de Especialidades Espíritu Santo · ECUniversidad Simón Bolívar · COBrigham and Women's Hospital · USLone Star College–Tomball · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSubclinical hypothyroidism (ScH) is an endocrine alteration that is related to cardiovascular risk factors, including those categorized as components of the Metabolic Syndrome (MS). However, findings in prior reports regarding an association between these alterations are inconsistent. The purpose of this study was to determine the relationship between both entities in adult subjects from Maracaibo City, Venezuela. MATERIALS AND

methodsThe Maracaibo City Metabolic Syndrome Prevalence Study is a descriptive, cross-sectional study with random and multistage sampling. In this substudy, 391 individuals of both genders were selected and TSH, free T3, and free T4 tests were performed as well as a complete lipid profile, fasting glycaemia, and insulin blood values. ScH was defined according to the National Health and Nutrition Examination Survey (NHANES) criteria: high TSH (≥4.12mUI/L) and normal free T4 (0.9-1,9 ng/dL) in subjects without personal history of thyroid disease. MS components were defined according to IDF/AHA/NHLBI/WHF/IAS/IASO-2009 criteria. A multiple logistic regression analysis was used to assess the relationship between MS components and ScH diagnosis.

resultsOf the evaluated population, 10.5% (n=41) was diagnosed with ScH, with a higher prevalence in women (female: 13.6% versus male: 7.7%;

conclusionThe relationship between ScH and MS in our population is dependent on the presence of hyperglycemia, specifically T2DM diagnosis, findings that vary from those previously reported in Latin American subjects.

Identifiers

PMID30151097
PMCPMC6087593
OpenAlexW2884828851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.