Evidence map›Paper›PMID 30150992›Full record

Trial reportFrontiers in immunology2018

Identification of

Guangyun Tan, Fengchao Xu, Hongxiao Song, Ye Yuan, Qingfei Xiao, Feng Ma, F Xiao-Feng Qin, Genhong Cheng

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. [Advances of TRIM superfamily proteins in chronic liver disease and hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. An Antiviral Role for TRIM14 in Ebola Virus Infection.The Journal of infectious diseases · 2023
    Article
  13. Baicalin inhibits the replication of the hepatitis B virus by targeting TRIM25.Journal of traditional and complementary medicine · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Guangyun TanDepartment of Immunology, Institute of Translational Medicine, The First Hospital of Jilin University, Changchun, China.
Fengchao XuDepartment of Immunology, Institute of Translational Medicine, The First Hospital of Jilin University, Changchun, China.
Hongxiao SongDepartment of Immunology, Institute of Translational Medicine, The First Hospital of Jilin University, Changchun, China.
Ye YuanDepartment of Medicine Laboratory, The First Hospital of Jilin University, Changchun, China.
Qingfei XiaoDepartment of Nephrology, The First Hospital, Jilin University, Changchun, China.
Feng MaSuzhou Institute of Systems Medicine, Suzhou, China.
F Xiao-Feng QinSuzhou Institute of Systems Medicine, Suzhou, China.
Genhong ChengDepartment of Immunology, Institute of Translational Medicine, The First Hospital of Jilin University, Changchun, China.
First Hospital of Jilin University · CNSuzhou Institute of Systems Medicine · CNJilin University · CNUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B virus (HBV) remains a major cause of hepatic disease that threatens human health worldwide. Type I IFN (IFN-I) therapy is an important therapeutic option for HBV patients. The antiviral effect of IFN is mainly mediated

Indexed as

Antiviral AgentsCarrier ProteinsClustered Regularly Interspaced Short Palindromic RepeatsHEK293 CellsHepatitis BHepatitis B virusHep G2 CellsHumansImmunotherapyInterferon Type IIntracellular Signaling Peptides and ProteinsPromoter Regions, GeneticProtein BindingReceptors, Pattern RecognitionSignal TransductionSTAT1 Transcription FactorAntiviral AgentsCarrier Proteinshepatitis B virus X proteinInterferon Type IIntracellular Signaling Peptides and ProteinsReceptors, Pattern RecognitionSTAT1 Transcription FactorTrans-ActivatorsTRIM14 protein, humanTripartite Motif ProteinsViral Regulatory and Accessory Proteinshepatitis B virus replicationhepatitis B virus X proteinSTAT1TRIM14type I IFN

Identifiers

PMID30150992
PMCPMC6100580
OpenAlexW2887533202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.