ArticleInternational journal of MS care
Effects of External Perturbations on Anticipatory and Compensatory Postural Adjustments in Patients with Multiple Sclerosis and a Fall History.
Article in International journal of MS care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Characterising anticipatory postural adjustments in turning a comparison between older adults and people with Parkinson's disease.Scientific reports · 2025Article
- Combined effects of Tai-Chi gait with mediolateral ground support perturbation on dynamic balance control.Sports medicine and health science · 2025Article
- I-BaR: integrated balance rehabilitation framework.Frontiers in neurorobotics · 2024Article
- Explanatory Capacity of Postural Control and Physical Fitness in Cognitive Impairment and Support Needs among Individuals with Intellectual Disabilities-A Cross-Sectional Pilot Study.Brain sciences · 2023Article
- A 3-DoF robotic platform for the rehabilitation and assessment of reaction time and balance skills of MS patients.PloS one · 2023Article
- Examining the Relationship Between Reactive Stepping Outcomes and Falls in People With Multiple Sclerosis.Physical therapy · 2022Article
- Postural Responses to Sudden Horizontal Perturbations in Tai Chi Practitioners.International journal of environmental research and public health · 2021Article
- Patterns of balance loss with systematic perturbations in Parkinson's disease and multiple sclerosis.NeuroRehabilitation · 2021Article
- Why Do Individuals with Cirrhosis Fall? A Mechanistic Model for Fall Assessment, Treatment, and Research.Digestive diseases and sciences · 2019Review
- An Initial Passive Phase That Limits the Time to Recover and Emphasizes the Role of Proprioceptive Information.Frontiers in neurology · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough previous studies have investigated postural adjustment mechanisms in patients with multiple sclerosis (MS), it seems that no study has yet investigated the relationship between anticipatory and compensatory postural adjustments (APAs and CPAs, respectively) and falls.
methodsSeventeen MS fallers, 17 MS nonfallers, and 15 controls were exposed to a series of expected and unexpected backward pull perturbations applied at the trunk level. The electrical activity of 12 leg and trunk muscles as well as center of pressure displacement were recorded.
resultsThe MS fallers had delayed muscle activity onsets compared with MS nonfallers and controls. In addition, a significantly lower level of muscle activity during APAs was detected in MS fallers compared with controls. Moreover, in the unexpected condition of perturbation, significantly smaller CPA was observed in MS fallers compared with controls. Both groups of patients with MS required more time to stabilize their center of pressure after both types of perturbations compared with controls.
conclusionsThe inability to produce efficient APAs and CPAs during perturbations may explain the high rates of postural instability and falls in patients with MS. Findings from this study provide a background for the development of perturbation-based training programs aimed at balance improvement and fall prevention by restoring mechanisms underlying balance impairments.
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Registered trials
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