Evidence map›Paper›PMID 30150751›Full record

ArticleScientific reports2018

A Kelch domain-containing KLHDC7B and a long non-coding RNA ST8SIA6-AS1 act oppositely on breast cancer cell proliferation via the interferon signaling pathway.

Gookjoo Jeong, Hansol Bae, Dawoon Jeong, Juyeon Ham, Sungbin Park, Hyeon Woo Kim, Han-Sung Kang, Sun Jung Kim

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  6. ST8SIA6-AS1, a novel lncRNA star in liver cancer.Frontiers in cell and developmental biology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Gookjoo JeongDepartment of Life Science, Dongguk University-Seoul, Goyang, Republic of Korea.
Hansol BaeDepartment of Life Science, Dongguk University-Seoul, Goyang, Republic of Korea.
Dawoon JeongDepartment of Life Science, Dongguk University-Seoul, Goyang, Republic of Korea.
Juyeon HamDepartment of Life Science, Dongguk University-Seoul, Goyang, Republic of Korea.
Sungbin ParkDepartment of Life Science, Dongguk University-Seoul, Goyang, Republic of Korea.
Hyeon Woo KimDepartment of Life Science, Dongguk University-Seoul, Goyang, Republic of Korea.
Han-Sung KangResearch Institute and Hospital, National Cancer Center, Goyang, Republic of Korea.
Sun Jung KimDepartment of Life Science, Dongguk University-Seoul, Goyang, Republic of Korea. sunjungk@dongguk.edu.
Dongguk University · KRNational Cancer Center · KR

Funding

National Research Foundation of Korea (NRF) 2016R1D1A1B01009235
6 · The paper itself

Abstract

In our previous study, the Kelch domain-containing 7B (KLHDC7B) was revealed to be hypermethylated at the promoter but upregulated in breast cancer. In this study, we identified a long non-coding RNA, ST8SIA6-AS1 (STAR1), whose expression was significantly associated with KLHDC7B in breast cancer (R

Indexed as

Adaptor Proteins, Signal TransducingBreast NeoplasmsCarrier ProteinsCell Line, TumorCell MovementCell ProliferationFlow CytometryGene Expression Regulation, NeoplasticHumansInterferon LambdaInterferonsInterleukinsMCF-7 CellsReverse Transcriptase Polymerase Chain ReactionRNA-Binding ProteinsRNA, Long NoncodingAdaptor Proteins, Signal TransducingCarrier ProteinsIFIT1 protein, humanInterferon Lambdainterferon-lambda, humanInterferonsInterleukinsRNA-Binding ProteinsRNA, Long NoncodingSTAT Transcription Factors

Identifiers

PMID30150751
PMCPMC6110865
OpenAlexW2888148669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.