Evidence map›Paper›PMID 30150733›Full record

ArticleNature microbiology2018

EXP2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via PTEX.

Matthias Garten, Armiyaw S Nasamu, Jacquin C Niles, Joshua Zimmerberg, Daniel E Goldberg, Josh R Beck

Open access · bronzeAbstract read
In one paragraph

Article in Nature microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 124 citations in OpenAlex.

  1. Article
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  8. Flp/Proceedings of the National Academy of Sciences of the United States of America · 2024
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  13. Review
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  15. Profile of Daniel E. Goldberg.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  16. Knock-sideways by inducible ER retrieval enables a unique approach for studyingProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Article
  18. Article
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Matthias GartenSection on Integrative Biophysics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-8660-1039
Armiyaw S NasamuDepartments of Medicine and Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.
Jacquin C NilesDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-6250-8796
Joshua ZimmerbergSection on Integrative Biophysics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA. zimmerbj@mail.nih.gov.ORCID http://orcid.org/0000-0002-1707-3789
Daniel E GoldbergDepartments of Medicine and Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA. dgoldberg@wustl.edu.ORCID http://orcid.org/0000-0003-3529-8399
Josh R BeckDepartments of Medicine and Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0001-6196-8689
National Institutes of Health · USWashington University in St. Louis · USIowa State University · USMassachusetts Institute of Technology · US

Funding

MIT Center for Integrative Synthetic BiologyP50GM098792 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI WEISS, RON · 2013 to 2017
$11.0M
PLASMEPSIN V FUNCTION IN MALARIA PARASITESR01AI047798 · NIAID · WASHINGTON UNIVERSITY · PI GOLDBERG, DANIEL E. · 2000 to 2015
$2.6M
Erythrocyte Subversion by Malaria Parasite Exported EffectorsR00HL133453 · NHLBI · IOWA STATE UNIVERSITY · PI BECK, JOSH RYAN · 2017 to 2019
$747k
Erythrocyte Subversion by Malaria Parasite Exported EffectorsK99HL133453 · NHLBI · WASHINGTON UNIVERSITY · PI BECK, JOSH RYAN · 2016 to 2017
$166k
NHLBI NIH HHS K99 HL133453NHLBI NIH HHS R00 HL133453NIAID NIH HHS R01 AI047798NIGMS NIH HHS P50 GM098792
6 · The paper itself

Abstract

Intraerythrocytic malaria parasites reside within a parasitophorous vacuolar membrane (PVM) generated during host cell invasion

Indexed as

ErythrocytesGene ExpressionHost-Parasite InteractionsLife Cycle StagesMalaria, FalciparumMutationPermeabilityPlasmodium falciparumProtein TransportProtozoan ProteinsSEC Translocation ChannelsVacuolesProtozoan ProteinsSEC Translocation Channels

Identifiers

PMID30150733
PMCPMC6158082
OpenAlexW2887998543

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.