ArticleScientific reports2018
Transcriptional shifts account for divergent resource allocation in feed efficient broiler chickens.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Genetic loci and key candidate genes associated with fatty acid composition in the breast muscle of Sansui ducks identified through GWAS.BMC genomics · 2026Article
- Effects of Genetic Selection on Growth, Nutritional Value, and Amino Acid Profiles of Breast Muscle and Blood in Black-Boned Chickens.Animals : an open access journal from MDPI · 2026Article
- Chronic cyclic mild heat stress downregulates genes encoding muscle structural components, contributing to reduced breast muscle mass in broiler chickens with minimal impact on meat quality.Journal of animal science · 2025Article
- Hepatic Transcriptomics of Broilers with Low and High Feed Conversion in Response to Caloric Restriction.Metabolites · 2024Article
- Dietary supplementation with Chlorella vulgaris in broiler chickens submitted to heat-stress: effects on growth performance and meat quality.Poultry science · 2024Article
- Genes involved in the cholecystokinin receptor signaling map were differentially expressed in the jejunum of steers with variation in residual feed intake.Veterinary and animal science · 2024Article
- RNA-Seq-based discovery of genetic variants and allele-specific expression of two layer lines and broiler chicken.Evolutionary applications · 2023Article
- Apolipoprotein H: a novel regulator of fat accumulation in duck myoblasts.Journal of animal science and technology · 2022Article
- Resistome Analysis of Global Livestock and Soil Microbiomes.Frontiers in microbiology · 2022Article
- Jejunal Transcriptomic Profiling for Differences in Feed Conversion Ratio in Slow-Growing Chickens.Animals : an open access journal from MDPI · 2021Article
- Time Course Transcriptomic Study Reveals the Gene Regulation During Liver Development and the Correlation With Abdominal Fat Weight in Chicken.Frontiers in genetics · 2021Article
- Identification of key genes and pathways associated with feed efficiency of native chickens based on transcriptome data via bioinformatics analysis.BMC genomics · 2020Article
- Effect of divergence in residual feed intake on expression of lipid metabolism-related genes in the liver of meat-type ducks1.Journal of animal science · 2019Article
- Feed Restriction Reveals Distinct Serum Metabolome Profiles in Chickens Divergent in Feed Efficiency Traits.Metabolites · 2019Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Considerable variation in feed efficiency (FE) has been observed in indigenous and selected meat-type chicken populations. Although this variation could be partially linked to extrinsic factors like diet, housing environment and microbiota, it further illustrates the existence of strong molecular mechanisms enabling the differential allocation of resources for various physiological processes. To further deepen the molecular basis of individual allocation capacity in male and female broilers, an RNA-seq experiment was conducted which based on a phenotyped chicken population divergent in FE. Transcriptional differences linked to FE were pronounced in intestinal and muscular tissue sites of male animals. Specifically, signalling pathways of farnesoid X receptor (FXR) and retinoid X receptor (RXR) might contribute to mediate individual FE. The transcriptional profiles suggested ACSBG2 (muscular lipid utilisation), ASBT (intestinal bile salt transport), CLEC2B (natural killer cell activation), HMGCS2 (jejunal, duodenal and muscular ketogenesis), and SCARB1 (jejunal lipid uptake) as potential mediators driving FE. Results indicate that improvements in FE exploit shifts in resource allocation which might occur at the expense of general immune responsiveness in high efficient male chickens. Consequently, to further improve FE traits and to explore causative molecular patterns, effects originating from sex-dimorphism in chickens need to be taken into consideration.
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