ArticleInternational journal of environmental research and public health2018
Cancer Risks in Vitiligo Patients: A Nationwide Population-Based Study in Taiwan.
Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Epidemiology and Comorbidity of Vitiligo in Germany: A Claims Data Analysis.Acta dermato-venereologica · 2026Article
- Cancer Risk in Vitiligo: No Evidence of Increased Prevalence-A Systematic Review and Meta-analysis.Dermatology and therapy · 2025Article
- Prevalence and incidence of comorbidities in patients with atopic dermatitis, psoriasis, alopecia areata, and vitiligo using a Japanese claims database.The Journal of dermatology · 2025Article
- Vitiligo and Prostate Cancer Correlation.Cureus · 2024Article
- Actinic keratoses and squamous cell carcinoma limited to photo-exposed skin in vitiligo vulgaris in pigmented skin type.BMJ case reports · 2024Article
- Anti-tumor immunity and vitiligo: from immune-related adverse reactions to protection from cancer.Immunotherapy · 2024Article
- Obstructing Stage IV Adenocarcinoma of the Transverse Colon in a Young Patient With Vitiligo.Cureus · 2023Article
- Visualizing novel connections and genetic similarities across diseases using a network-medicine based approach.Scientific reports · 2022Article
- Reduced risk of skin cancer and internal malignancies in vitiligo patients: a retrospective population-based cohort study in Taiwan.Scientific reports · 2021Article
- Cancer risks in patients with vitiligo: a Mendelian randomization study.Journal of cancer research and clinical oncology · 2020Article
- Risk of skin cancer in patients with vitiligo in Denmark: A nationwide cohort study.JAAD international · 2020Article
- Association of Functional Polymorphism in Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) Gene with Vitiligo.Biomarker insights · 2020Article
- Iris metastasis as the initial presentation of upper gastrointestinal tract carcinoma: a case report.Journal of medical case reports · 2019Article
- The Risk of Mortality among Psoriatic Patients with Varying Severity: A Nationwide Population-Based Cohort Study in Taiwan.International journal of environmental research and public health · 2018Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitiligo is an autoimmune disease characterized by destruction of melanocytes and associated with other autoimmune disease. Whether the dysregulation of immune system enhances oncogenesis or not remains obscure. Until now, no nationwide population-based study has been conducted regarding this. As such, this paper aims to clarify cancer risk in vitiligo patients. A retrospective nationwide population-based cohort study between 2000 and 2010 was performed based on data from the National Health Insurance Research Database of Taiwan. Standardized incidence ratios (SIRs) of cancers were analyzed. Among the 12,391 vitiligo patients (5364 males and 7027 females) and 48,531.09 person-years of observation, a total of 345 cancers were identified. Significantly increased SIRs were observed for prostate cancer in male patients, thyroid cancer and breast cancer in female patients and bladder cancers in both male and female patients. Unfortunately, the low incidence rate of certain cancers limited the power of our statistical analyses. This study demonstrated the patterns of malignancies in vitiligo patients of Taiwan. Compared with the general population, male patients had higher risks of prostate cancer and female patients had higher risks of thyroid cancer and breast cancer. The risks of bladder cancer were also increased in both male and female patients.
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