Evidence map›Paper›PMID 30150559›Full record

ArticleViruses2018

Antiviral Effect of Resveratrol in Piglets Infected with Virulent Pseudorabies Virus.

Xinghong Zhao, Wenzhi Tong, Xu Song, Renyong Jia, Lixia Li, Yuanfeng Zou, Changliang He, Xiaoxia Liang, Cheng Lv, Bo Jing and 6 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Xinghong ZhaoNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. zhaoxinghong8@163.com.
Wenzhi TongNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. 13056679601@163.com.
Xu SongNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. songx@sicau.edu.cn.
Renyong JiaKey laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, China. cqrc_jry@163.com.
Lixia LiNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. lilixia905@163.com.
Yuanfeng ZouNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. yuanfengzou@sicau.edu.cn.ORCID 0000-0002-3116-1478
Changliang HeNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. lorri190@126.com.
Xiaoxia LiangNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. liangxiaoxia@sicau.edu.cn.
Cheng LvNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. lvcheng1980@163.com.
Bo JingNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. jingbooo@163.com.
Juchun LinNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. juchunlin@126.com.
Lizi YinNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. yinlizi@hotmail.com.
Gang YeNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. yegang800206@163.com.
Guizhou YueCollege of Science, Sichuan Agricultural University, Ya'an 625014, China. yueguizhou@sicau.edu.cn.
Yin WangKey laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, China. yaanwangyin@tom.com.
Zhongqiong YinNatural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. yinzhongq@163.com.
Sichuan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudorabies virus (PRV) is one of the most important pathogens of swine, resulting in devastating disease and economic losses worldwide. Nevertheless, there are currently no antiviral drugs available for PRV infection. Resveratrol (Res) was identified to exert its antiviral activity by inhibiting the PRV replication in preliminary investigations. In our previous study, we found that Res has anti-PRV activity in vitro. Here, we show that Res can effectively reduce the mortality and increase the growth performance of PRV-infected piglets. After Res treatment, the viral loads significantly (

Indexed as

AnimalsAntiviral AgentsCytokinesHerpesvirus 1, SuidHumansInflammationPseudorabiesResveratrolSwineSwine DiseasesViral LoadVirulenceVirus ReplicationAntiviral AgentsCytokinesResveratrolantiviral activitypigletsresveratrolvirulent pseudorabies virus

Identifiers

PMID30150559
PMCPMC6164078
OpenAlexW2889299623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.