Evidence map›Paper›PMID 30150543›Full record

ArticleMolecules (Basel, Switzerland)2018

Synthesis and Biological Evaluation of Novel Alkyl Amine Substituted Icariside II Derivatives as Potential Anticancer Agents.

Tong Wu, Ting Li, Ya-Nan Kang, Li Liu, Xi-Man Wang, Jin-Shuai Lan, Yue Ding, Tong Zhang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tong WuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. 13501919930@163.com.
Ting LiExperiment Center for Teaching and Learning, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. liting201304@163.com.
Ya-Nan KangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. yanankk1993@outlook.com.
Li LiuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. 15216678512@163.com.
Xi-Man WangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. 15000655647@126.com.
Jin-Shuai LanExperiment Center for Teaching and Learning, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. lanjinshuai_shut@126.com.
Yue DingSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. dingyue-2001@hotmail.com.
Tong ZhangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. zhangtongshutcm@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of novel alkyl amine-substituted icariside II (ICA II) derivatives were synthesized by Mannich reactions at the 6-C position (compounds

Indexed as

AminesAntineoplastic AgentsApoptosisCell CycleCell Line, TumorCell ProliferationCell SurvivalFlavonoidsHumansMagnetic Resonance SpectroscopyMolecular StructureStructure-Activity RelationshipAminesAntineoplastic Agentsbaohuoside IFlavonoidsanticancerapoptosisicariside IIstructure-activity relationship

Identifiers

PMID30150543
PMCPMC6225249

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.