ArticleMaterials (Basel, Switzerland)2018
Tuning Nano-Amorphous Calcium Phosphate Content in Novel Rechargeable Antibacterial Dental Sealant.
Article in Materials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
20 citing papers in PubMed, 48 citations in OpenAlex.
- Review
- Evaluation of bioactive restorative materials on cell viability using direct and extract methods.Brazilian oral research · 2026Article
- Evaluation of the remineralization potential of bioactive materials using different methods.Scientific reports · 2025Article
- Article
- Comparison between Different Bulk-Fill and Incremental Composite Materials Used for Class II Restorations in Primary and Permanent Teeth: In Vitro Assessments.Materials (Basel, Switzerland) · 2023Article
- Exploring the Potential of Nanotechnology in Pediatric Healthcare: Advances, Challenges, and Future Directions.Pharmaceutics · 2023Review
- Inorganic Compounds as Remineralizing Fillers in Dental Restorative Materials: Narrative Review.International journal of molecular sciences · 2023Review
- Remineralizing Effects of Resin-Based Dental Sealants: A Systematic Review of In Vitro Studies.Polymers · 2022Review
- Development of antibacterial composite resin containing chitosan/fluoride microparticles as pit and fissure sealant to prevent caries.Journal of oral microbiology · 2022Article
- Flexural Strength, Elastic Modulus and Remineralizing Abilities of Bioactive Resin-Based Dental Sealants.Polymers · 2021Article
- Dental Sealant Composition-Retention Assessment in Young Permanent Molars.Materials (Basel, Switzerland) · 2021Article
- The Antibacterial Effects of Resin-Based Dental Sealants: A Systematic Review of In Vitro Studies.Materials (Basel, Switzerland) · 2021Review
- Bibliometric Analysis of Literature Published on Antibacterial Dental Adhesive from 1996-2020.Polymers · 2020Review
- Novel Crown Cement Containing Antibacterial Monomer and Calcium Phosphate Nanoparticles.Nanomaterials (Basel, Switzerland) · 2020Article
- Emerging Contact-Killing Antibacterial Strategies for Developing Anti-Biofilm Dental Polymeric Restorative Materials.Bioengineering (Basel, Switzerland) · 2020Review
- Applications of nano-materials in diverse dentistry regimes.RSC advances · 2020Review
- Dental Sealant Empowered by 1,3,5-Tri Acryloyl Hexahydro-1,3,5-Triazine and α-Tricalcium Phosphate for Anti-Caries Application.Polymers · 2020Article
- A Novel Dental Sealant Containing Dimethylaminohexadecyl Methacrylate Suppresses the Cariogenic Pathogenicity ofInternational journal of molecular sciences · 2019Article
- Application of Antimicrobial Nanoparticles in Dentistry.Molecules (Basel, Switzerland) · 2019Review
- Toward dental caries: Exploring nanoparticle-based platforms and calcium phosphate compounds for dental restorative materials.Bioactive materials · 2019Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dental sealants with antibacterial and remineralizing properties are promising for caries prevention among children and adolescents. The application of nanotechnology and polymer development have enabled nanoparticles of amorphous calcium phosphate (NACP) and dimethylaminohexadecyl methacrylate (DMAHDM) to emerge as anti-caries strategies via resin-based dental materials. Our objectives in this study were to (1) incorporate different mass fractions of NACP into a parental rechargeable and antibacterial sealant; (2) investigate the effects on mechanical performance, and (3) assess how the variations in NACP concentration would affect the calcium (Ca) and phosphate (PO₄) ion release and re-chargeability over time. NACP were synthesized using a spray-drying technique and incorporated at mass fractions of 0, 10, 20 and 30%. Flexural strength, flexural modulus, and flowability were assessed for mechanical and physical performance. Ca and PO₄ ion release were measured over 70 days, and three ion recharging cycles were performed for re-chargeability. The impact of the loading percentage of NACP upon the sealant's performance was evaluated, and the optimized formulation was eventually selected. The experimental sealant at 20% NACP had flexural strength and flexural modulus of 79.5 ± 8.4 MPa and 4.2 ± 0.4 GPa, respectively, while the flexural strength and flexural modulus of a commercial sealant control were 70.7 ± 5.5 MPa (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.