Evidence map›Paper›PMID 30150529›Full record

SynthesisNutrients2018

Single Nucleotide Polymorphisms in Vitamin D Receptor Gene Affect Birth Weight and the Risk of Preterm Birth: Results From the "Mamma & Bambino" Cohort and A Meta-Analysis.

Martina Barchitta, Andrea Maugeri, Maria Clara La Rosa, Roberta Magnano San Lio, Giuliana Favara, Marco Panella, Antonio Cianci, Antonella Agodi

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 4 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 4 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Observational
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  10. The Role of Genetics in Preterm Birth.Reproductive sciences (Thousand Oaks, Calif.) · 2023
    Review
  11. Article
  12. Article
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  16. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Martina BarchittaDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, via S. Sofia, 87, 95123 Catania, Italy. martina.barchitta@unict.it.ORCID 0000-0002-0905-5003
Andrea MaugeriDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, via S. Sofia, 87, 95123 Catania, Italy. andreamaugeri88@gmail.com.ORCID 0000-0003-2655-8574
Maria Clara La RosaDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, via S. Sofia, 87, 95123 Catania, Italy. mariclalarosa@gmail.com.
Roberta Magnano San LioDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, via S. Sofia, 87, 95123 Catania, Italy. robimagnano@gmail.com.
Giuliana FavaraDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, via S. Sofia, 87, 95123 Catania, Italy. giuliana.favara@gmail.com.
Marco PanellaDepartment of General Surgery and Medical Surgical Specialties, University of Catania, Via S. Sofia, 78, 95123 Catania, Italy. mpanella@unict.it.
Antonio CianciDepartment of General Surgery and Medical Surgical Specialties, University of Catania, Via S. Sofia, 78, 95123 Catania, Italy. acianci@unict.it.
Antonella AgodiDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, via S. Sofia, 87, 95123 Catania, Italy. agodia@unict.it.ORCID 0000-0002-4405-8162
University of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of vitamin D receptor gene (VDR) polymorphisms on adverse pregnancy outcomes-including preterm birth (PTB), low birth weight and small for gestational age-is currently under debate. We investigated 187 mother-child pairs from the Italian "Mamma & Bambino" cohort to evaluate the association of maternal VDR polymorphisms-BsmI, ApaI, FokI and TaqI-with neonatal anthropometric measures and the risk of PTB. To corroborate our results, we conducted a meta-analysis of observational studies. For the FokI polymorphism, we showed that gestational duration and birth weight decreased with increasing number of A allele (

Indexed as

Infant, Low Birth WeightPolymorphism, Single NucleotideAdolescentAdultBirth WeightFemaleGenetic Association StudiesGenetic Predisposition to DiseaseGestational AgeHumansInfant, NewbornItalyMiddle AgedPhenotypePremature BirthReceptors, CalcitriolReceptors, CalcitriolVDR protein, humanbirth cohortgestational durationpregnancyvitamin D

Identifiers

PMID30150529
PMCPMC6164379
OpenAlexW2888838782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.