Evidence map›Paper›PMID 30150432›Full record

ArticleIn vivo (Athens, Greece)

Endothelial Lipase Gene Polymorphism (584 C/T) in Coronary Artery Patients Among a Turkish Population.

Levent Akman Solim, Izgi Ayçil Gencan, Behiç Çelik, Alara Ataacar, Umut Koç, Beyza Büyükören, Gizem Güngör, Selim Isbir

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Levent Akman SolimFaculty of Medicine, Yeditepe University, Istanbul, Turkey leventsolim@gmail.com.
Izgi Ayçil GencanFaculty of Medicine, Yeditepe University, Istanbul, Turkey.
Behiç ÇelikFaculty of Medicine, Yeditepe University, Istanbul, Turkey.
Alara AtaacarFaculty of Medicine, Yeditepe University, Istanbul, Turkey.
Umut KoçFaculty of Medicine, Yeditepe University, Istanbul, Turkey.
Beyza BüyükörenFaculty of Medicine, Yeditepe University, Istanbul, Turkey.
Gizem GüngörFaculty of Medicine, Yeditepe University, Istanbul, Turkey.
Selim IsbirDepartment of Cardiovascular Surgery, Marmara University Pendik Education and Research Hospital, Istanbul, Turkey.
Yeditepe University · TRMarmara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThe endothelial lipase gene (LIPG) has a major role in regulating high density lipoprotein cholesterol (HDL-C), therefore this study investigated whether LIPG is associated with coronary artery disease (CAD) in a Turkish population. MATERIALS AND

methodsThe LIPG (584 C/T) mutation was analyzed in 74 CAD patients and 73 controls.

resultsThere was a significant difference between the two groups regarding the mutant T allele frequencies (χ

conclusionThe endothelial lipase gene (584 C/T) T allele might be protective in association with coronary artery disease. Therefore, LIPG gene is related to risk for CAD in the Turkish population probably through altering HDL-C metabolism.

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideAgedAllelesBiomarkersCase-Control StudiesCoronary Artery DiseaseFemaleGene FrequencyGenetic Association StudiesGenotypeHumansLipaseMaleMiddle AgedOdds RatioBiomarkersLipaseLIPG protein, humanCoronary artery diseaseLIPG (584 C/T)polymorphism

Identifiers

PMID30150432
PMCPMC6199614
OpenAlexW2889003914

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.