Trial reportProceedings of the National Academy of Sciences of the United States of America2018
Default mode network can support the level of detail in experience during active task states.
Trial report in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 137 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
137 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Tasks activating the default mode network map multiple functional systems.Brain structure & function · 2022Pooled it
- The Interaction of the Dorsolateral and Ventromedial Prefrontal Cortex During Mind Wandering.Brain topography · 2023Trial
- Medial temporal default mode network selectively encodes autobiographical visual imagery.Science advances · 2026Article
- Resolving the Abstract-Concrete Paradox in the Angular Gyrus: A Multimethod Investigation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- The Association Between Loss of Consciousness and the Default Mode Network at the Chronic Stage of Diffuse Axonal Injury: A Diffusion Tensor Imaging Study.Journal of clinical medicine · 2026Article
- Differences in the Subcortical White Matter Integrity Based on the Disorder of Consciousness at the Chronic Stage of Diffuse Axonal Injury: A Tract-Based Spatial Statistics Study.Medicina (Kaunas, Lithuania) · 2026Article
- Ongoing thoughts at rest reflect functional brain organization and behaviour.Nature human behaviour · 2026Article
- Real-time fMRI-triggered experience-sampling: a proof-of-concept study.bioRxiv : the preprint server for biology · 2026Article
- Neurochemical Correlates of Mind-Wandering and Meta-Awareness.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Executive Dysfunction and Depression Risk in Adolescence: Functional-MRI Analysis of Transient Network States During a Working Memory Task.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Task-Dependent Visual Topographic Connectivity in the Human Cerebellum.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Social mind at rest: resting-state connectivity associated with social thought relates to friendship quality.Social cognitive and affective neuroscience · 2026Article
- Does nonsense make sense? A springboard to studying dynamic reconfiguration of large-scale networks during semantic and intonation speech processing.NeuroImage · 2026Article
- Avoidance habit learning in adolescents and young women with anorexia nervosa: an fMRI study.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Cortical Network Activity Associated With Different Types of Word Recognition Errors by Older Adults.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Alcohol Cues Elicit Differences in Brain Activation Patterns of Abstinent Men and Women with Alcohol Use Disorders.Neuropsychiatric disease and treatment · 2026Article
- Behavioral, experiential, and physiological signatures of mind blanking.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Untested Assumptions and Tenuous Evidence: A Critique of the Dual-Process Account of Moral Judgment.Behavioral sciences (Basel, Switzerland) · 2025Review
- A dynamic framework of brain functional patterns shaped by spontaneous thoughts beyond the default mode network.Scientific reports · 2025Article
- Structure-Based Medical Acupuncture: New Perspective on an Ancient Technique.Medical acupuncture · 2025Article
77 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regions of transmodal cortex, in particular the default mode network (DMN), have historically been argued to serve functions unrelated to task performance, in part because of associations with naturally occurring periods of off-task thought. In contrast, contemporary views of the DMN suggest it plays an integrative role in cognition that emerges from its location at the top of a cortical hierarchy and its relative isolation from systems directly involved in perception and action. The combination of these topographical features may allow the DMN to support abstract representations derived from lower levels in the hierarchy and so reflect the broader cognitive landscape. To investigate these contrasting views of DMN function, we sampled experience as participants performed tasks varying in their working-memory load while inside an fMRI scanner. We used self-report data to establish dimensions of thought that describe levels of detail, the relationship to a task, the modality of thought, and its emotional qualities. We used representational similarity analysis to examine correspondences between patterns of neural activity and each dimension of thought. Our results were inconsistent with a task-negative view of DMN function. Distinctions between on- and off-task thought were associated with patterns of consistent neural activity in regions adjacent to unimodal cortex, including motor and premotor cortex. Detail in ongoing thought was associated with patterns of activity within the DMN during periods of working-memory maintenance. These results demonstrate a contribution of the DMN to ongoing cognition extending beyond task-unrelated processing that can include detailed experiences occurring under active task conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.