Evidence map›Paper›PMID 30150382›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation.

Xueqin Li, C Jake Harris, Zhenhui Zhong, Wei Chen, Rui Liu, Bei Jia, Zonghua Wang, Sisi Li, Steven E Jacobsen, Jiamu Du

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
24.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 118 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Features of DNA methylome in Capsicum spp.Epigenetics & chromatin · 2025
    Article
  6. Article
  7. A chromatin-linked CPL2-PHD2/3 module sustains multiple DNA methylation pathways and Polycomb silencing.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. RNA mNature plants · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Epigenetics in the modern era of crop improvements.Science China. Life sciences · 2025
    Review
  13. Review
  14. The histone variant H2A.W restricts heterochromatic crossovers inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Xueqin LiNational Key Laboratory of Plant Molecular Genetics, Chinese Academy of Sciences Center for Excellence in Molecular Plant Sciences, Shanghai Center for Plant Stress Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 201602 Shanghai, China.
C Jake HarrisDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095.
Zhenhui ZhongDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095.
Wei ChenNational Key Laboratory of Plant Molecular Genetics, Chinese Academy of Sciences Center for Excellence in Molecular Plant Sciences, Shanghai Center for Plant Stress Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 201602 Shanghai, China.
Rui LiuNational Key Laboratory of Plant Molecular Genetics, Chinese Academy of Sciences Center for Excellence in Molecular Plant Sciences, Shanghai Center for Plant Stress Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 201602 Shanghai, China.
Bei JiaNational Key Laboratory of Plant Molecular Genetics, Chinese Academy of Sciences Center for Excellence in Molecular Plant Sciences, Shanghai Center for Plant Stress Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 201602 Shanghai, China.
Zonghua WangState Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, 350002 Fuzhou, China.
Sisi LiDepartment of Biology, Southern University of Science and Technology of China, Shenzhen, 518055 Guangdong, China.
Steven E JacobsenDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095; jacobsen@ucla.edu jmdu@sibs.ac.cn.
Jiamu DuNational Key Laboratory of Plant Molecular Genetics, Chinese Academy of Sciences Center for Excellence in Molecular Plant Sciences, Shanghai Center for Plant Stress Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 201602 Shanghai, China; jacobsen@ucla.edu jmdu@sibs.ac.cn.ORCID 0000-0002-1337-0786
Chinese Academy of Sciences · CNUniversity of California, Los Angeles · USHoward Hughes Medical Institute · USMinjiang University · CNSouthern University of Science and Technology · CN

Funding

Genetics of DNA methylation patterning of arabidopsis.R37GM060398 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JACOBSEN, STEVEN E · 2009 to 2018
$3.0M
Genetics of DNA Methylation Patterning of ArabidopsisR01GM060398 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JACOBSEN, STEVEN E · 2000 to 2008
$2.2M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM060398NIGMS NIH HHS R37 GM060398
6 · The paper itself

Abstract

DNA methylation functions in gene silencing and the maintenance of genome integrity. In plants, non-CG DNA methylation is linked through a self-reinforcing loop with histone 3 lysine 9 dimethylation (H3K9me2). The plant-specific SUPPRESSOR OF VARIEGATION 3-9 HOMOLOG (SUVH) family H3K9 methyltransferases (MTases) bind to DNA methylation marks and catalyze H3K9 methylation. Here, we analyzed the structure and function of

Indexed as

DNA MethylationArabidopsisArabidopsis ProteinsBase SequenceCrystallography, X-RayDNAHistone-Lysine N-MethyltransferaseHistonesLysineMethylationModels, MolecularNucleic Acid ConformationPlants, Genetically ModifiedProtein BindingProtein ConformationArabidopsis ProteinsDNAHistone-Lysine N-MethyltransferaseHistonesLysineSUVH6 protein, ArabidopsisDNA methylationH3K9me2histone methyltransferaseplantSUVH6

Identifiers

PMID30150382
PMCPMC6140468
OpenAlexW2889348647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.