Evidence map›Paper›PMID 30150255›Full record

ArticleInfection and immunity2018

Screening for Th17-Dependent Pneumococcal Vaccine Antigens: Comparison of Murine and Human Cellular Immune Responses.

Ying-Jie Lu, Elizabeth Oliver, Fan Zhang, Caroline Pope, Adam Finn, Richard Malley

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ying-Jie LuDivision of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA Yingjie.lu@childrens.harvard.edu.
Elizabeth OliverSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.
Fan ZhangDivision of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Caroline PopeSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.
Adam Finn *School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.
Richard Malley *Division of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
University of Bristol · GBHarvard University · USBoston Children's Hospital · US

Funding

Identification of protective pneumococcal antigens from a surface protein libraryR21AI103480 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI LU, YINGJIE · 2013 to 2014
$413k
NIAID NIH HHS R21 AI103480
6 · The paper itself

Abstract

Conjugate vaccines against

Indexed as

AnimalsAntigens, BacterialCarrier StateHumansInterleukin-17Interleukin-22InterleukinsLeukocytes, MononuclearMice, Inbred C57BLModels, AnimalPneumococcal InfectionsPneumococcal VaccinesAntigens, BacterialInterleukin-17Interleukin-22InterleukinsPneumococcal Vaccinesantigen discoverycolonizationStreptococcus pneumoniaeTh17

Identifiers

PMID30150255
PMCPMC6204694
OpenAlexW2888146609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.