Evidence map›Paper›PMID 30149603›Full record

ArticleBiomolecules2018

Recombinant Fusion Protein Joining E Protein Domain III of Tick-Borne Encephalitis Virus and HSP70 of

Vasily Golotin, Nina Sanina, Ludmila Davydova, Natalia Chopenko, Andrey Mazeika, Manuel Roig, Valery Shnyrov, Vladimir N Uversky, Eduard Kostetsky

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Vasily GolotinDepartment of Biochemistry, Microbiology and Biotechnology, Far Eastern Federal University, Sukhanov St., 8, Vladivostok 690091, Russia. golotin@bk.ru.
Nina SaninaDepartment of Biochemistry, Microbiology and Biotechnology, Far Eastern Federal University, Sukhanov St., 8, Vladivostok 690091, Russia. sanina.nm@dvfu.ru.ORCID 0000-0001-5838-691X
Ludmila DavydovaDepartment of Biochemistry, Microbiology and Biotechnology, Far Eastern Federal University, Sukhanov St., 8, Vladivostok 690091, Russia. l.vorobushek@mail.ru.
Natalia ChopenkoDepartment of Biochemistry, Microbiology and Biotechnology, Far Eastern Federal University, Sukhanov St., 8, Vladivostok 690091, Russia. natali_1389@mail.ru.ORCID 0000-0003-0244-517X
Andrey MazeikaDepartment of Biochemistry, Microbiology and Biotechnology, Far Eastern Federal University, Sukhanov St., 8, Vladivostok 690091, Russia. nikandrei@inbox.ru.
Manuel RoigDepartamento de Química Física, Facultad de Ciencias Químicas, Universidad de Salamanca, Plaza de los Caìdos s/n, 37008 Salamanca, Spain. mgr@usal.es.
Valery ShnyrovDepartamento de Bioquímica y Biología Molecular, Facultad de Biología, Universidad de Salamanca, Plaza Doctores de la Reina s/n, 37007 Salamanca, Spain. shnyrov@usal.es.ORCID 0000-0003-3470-9774
Vladimir N UverskyDepartment of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd. MDC07, Tampa, FL 33612, USA. vuversky@health.usf.edu.ORCID 0000-0002-4037-5857
Eduard KostetskyDepartment of Biochemistry, Microbiology and Biotechnology, Far Eastern Federal University, Sukhanov St., 8, Vladivostok 690091, Russia. kostetskiy.yeya@dvfu.ru.
Far Eastern Federal University · RUUniversidad de Salamanca · ESUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Domain III (DIII) of the tick-borne encephalitis virus (TBEV) protein E contains epitopes, which induce antibodies capable of neutralizing the virus. To enhance the immunogenicity of this protein, which has a low molecular weight, the aim of the present work was to express, isolate, and characterize a chimeric protein based on the fusion of the bacterial chaperone HSP70 of

Indexed as

Encephalitis Viruses, Tick-BorneYersinia pseudotuberculosisAnimalsAntigensHSP70 Heat-Shock ProteinsISCOMsMaleMiceProtein DomainsRecombinant Fusion ProteinsViral Envelope ProteinsAntigensHSP70 Heat-Shock ProteinsISCOMsRecombinant Fusion ProteinsViral Envelope Proteinsdifferential scanning calorimetrydomain IIIenvelope proteinflavivirus vaccinefusion proteinHSP70intrinsic fluorescenceTBEV

Identifiers

PMID30149603
PMCPMC6164642
OpenAlexW2888504678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.