ArticleBiomolecules2018
Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1.
Article in Biomolecules, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Cryo-EM reveals thatProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Queuosine tRNA modification regulates translational adaptation and virulence of Leishmania mexicana.PLoS biology · 2026Article
- tRNA modifications in cancer: from molecular mechanisms to clinical translation.Biomarker research · 2026Review
- The exercise-microbiota-queuine-tRNA axis in Parkinson's disease: evidence, uncertainties, and experimental priorities.Frontiers in neuroscience · 2026Review
- Queuosine salvage inMicrobiology (Reading, England) · 2024Article
- Queuosine Salvage inbioRxiv : the preprint server for biology · 2024Article
- Translational response to mitochondrial stresses is orchestrated by tRNA modifications.bioRxiv : the preprint server for biology · 2024Article
- 7-Deazaguanines in DNA: functional and structural elucidation of a DNA modification system.Nucleic acids research · 2023Article
- Functional integration of a semi-synthetic azido-queuosine derivative into translation and a tRNA modification circuit.Nucleic acids research · 2022Article
- Toxicological Properties of 7-Methylguanine, and Preliminary Data on its Anticancer Activity.Frontiers in pharmacology · 2022Article
- Article
- MCTS1 promotes the development of lung adenocarcinoma by regulating E2F1 expression.Oncology letters · 2021Article
- The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity.Nucleic acids research · 2021Article
- Article
- Enhanced expression of queuine tRNA-ribosyltransferase 1 (Annals of translational medicine · 2020Article
- Enzymatic covalent labeling of RNA with RNA transglycosylation at guanosine (RNA-TAG).Methods in enzymology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
RNA modifications have been implicated in diverse and important roles in all kingdoms of life with over 100 of them present on tRNAs. A prominent modification at the wobble base of four tRNAs is the 7-deaza-guanine derivative queuine which substitutes the guanine at position 34. This exchange is catalyzed by members of the enzyme class of tRNA guanine transglycosylases (TGTs). These enzymes incorporate guanine substituents into tRNA
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