Evidence map›Paper›PMID 30149561›Full record

ReviewInternational journal of molecular sciences2018

The Promise of Novel Biomarkers for Head and Neck Cancer from an Imaging Perspective.

Loredana G Marcu, Paul Reid, Eva Bezak

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Current Role of Delta Radiomics in Head and Neck Oncology.International journal of molecular sciences · 2023
    Review
  6. Cannot Target What Cannot Be Seen: Molecular Imaging of Cancer Stem Cells.International journal of molecular sciences · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Clinical validity of saliva and novel technology for cancer detection.Biochimica et biophysica acta. Reviews on cancer · 2019
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Loredana G MarcuFaculty of Science, University of Oradea, 410087 Oradea, Romania. loredana@marcunet.com.ORCID 0000-0002-6703-979X
Paul ReidCancer Research Institute and School of Health Sciences, University of South Australia, Adelaide, SA 5001, Australia. paul.reid@mymail.unisa.edu.au.ORCID 0000-0002-2210-878X
Eva BezakCancer Research Institute and School of Health Sciences, University of South Australia, Adelaide, SA 5001, Australia. Eva.Bezak@unisa.edu.au.ORCID 0000-0002-1315-1735

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is an agreed fact that overall survival among head and neck cancer patients has increased over the last decade. Several factors however, are still held responsible for treatment failure requiring more in-depth evaluation. Among these, hypoxia and proliferation-specific parameters are the main culprits, along with the more recently researched cancer stem cells. This paper aims to present the latest developments in the field of biomarkers for hypoxia, stemness and tumour proliferation, from an imaging perspective that includes both Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) as well as functional magnetic resonance imaging (MRI). Quantitative imaging of biomarkers is a prerequisite for accurate treatment response assessment, bringing us closer to the highly needed personalised therapy.

Indexed as

BiomarkersDiagnostic ImagingCell ProliferationHead and Neck NeoplasmsHumansHypoxiaMagnetic Resonance ImagingMolecular ImagingNeoplastic Stem CellsPositron-Emission TomographyTomography, Emission-Computed, Single-PhotonBiomarkerscancer stem cellshypoxiaMRIPETproliferationradioresistanceSPECT

Identifiers

PMID30149561
PMCPMC6165113

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.