Evidence map›Paper›PMID 30149546›Full record

ArticleNutrients2018

Yeast-Derived Recombinant Avenanthramides Inhibit Proliferation, Migration and Epithelial Mesenchymal Transition of Colon Cancer Cells.

Federica Finetti, Andrea Moglia, Irene Schiavo, Sandra Donnini, Giovanni Nicolao Berta, Federica Di Scipio, Andrea Perrelli, Claudia Fornelli, Lorenza Trabalzini, Saverio Francesco Retta

Abstract readComparative Study
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Multiple Antioxidative and Bioactive Molecules of Oats (Antioxidants (Basel, Switzerland) · 2021
    Review
  8. Article
  9. Antioxidants (Basel, Switzerland) · 2020
    Article
  10. Overview of the Anticancer Profile of Avenanthramides from Oat.International journal of molecular sciences · 2019
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Federica FinettiDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy. finetti2@unisi.it.
Andrea MogliaCCM Italia research network (www.ccmitalia.unito.it), 10043 Torino, Italy. andrea.moglia@unito.it.ORCID 0000-0001-7431-844X
Irene SchiavoDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy. schiavoirene@gmail.com.
Sandra DonniniDepartment of Life Sciences, University of Siena, 53100 Siena, Italy. sandra.donnini@unisi.it.
Giovanni Nicolao BertaDepartment of Clinical and Biological Sciences, University of Torino, 10043 Torino, Italy. giovanni.berta@unito.it.
Federica Di ScipioDepartment of Clinical and Biological Sciences, University of Torino, 10043 Torino, Italy. federica.discipio@unito.it.
Andrea PerrelliCCM Italia research network (www.ccmitalia.unito.it), 10043 Torino, Italy. andrea.perrelli@unito.it.
Claudia FornelliCCM Italia research network (www.ccmitalia.unito.it), 10043 Torino, Italy. claudia.fornelli@unito.it.
Lorenza TrabalziniDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy. lorenza.trabalzini@unisi.it.
Saverio Francesco RettaCCM Italia research network (www.ccmitalia.unito.it), 10043 Torino, Italy. francesco.retta@unito.it.ORCID 0000-0001-9761-2959

Funding

Telethon GGP15219
6 · The paper itself

Abstract

Avenanthramides (Avns), polyphenols found exclusively in oats, are emerging as promising therapeutic candidates for the treatment of several human diseases, including colon cancer. By engineering a

Indexed as

AdenocarcinomaAntineoplastic AgentsCell MovementCell ProliferationColorectal NeoplasmsCyclin-Dependent Kinase Inhibitor p21Cyclin-Dependent Kinase Inhibitor p27Epithelial-Mesenchymal TransitionHT29 CellsHumansNeoplasm Invasivenessortho-AminobenzoatesSaccharomyces cerevisiaeSignal TransductionTumor Suppressor Protein p53Antineoplastic AgentsCDKN1A protein, humanCDKN1B protein, humanCyclin-Dependent Kinase Inhibitor p21Cyclin-Dependent Kinase Inhibitor p27ortho-AminobenzoatesTP53 protein, humanTumor Suppressor Protein p53chemopreventioncolon cancer cellsepithelial-mesenchymal transition (EMT)migrationnutraceuticalsoats avenanthramidespolyphenolsproliferationyeast-derived recombinant avenanthramides

Identifiers

PMID30149546
PMCPMC6165333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.