ArticleNutrients2018
Biomarkers of Systemic Inflammation and Growth in Early Infancy are Associated with Stunting in Young Tanzanian Children.
Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Pro/synbiotics reduce systemic inflammation and improve gut health in Kenyan infants: An open label, randomized, 4-arm, phase II trial.Cell reports. Medicine · 2026Trial
- Effect of lipid-based nutrient supplements on morbidity among children with stunting: secondary analysis of a randomized trial in Uganda.European journal of clinical nutrition · 2025Trial
- Trial
- Stunting Status and Exposure to Infection and Inflammation in Early Life Shape Antibacterial Immune Cell Function Among Zimbabwean Children.Frontiers in immunology · 2022Trial
- Markers of Systemic Inflammation and Environmental Enteric Dysfunction Are Not Reduced by Zinc or Multivitamins in Tanzanian Infants: A Randomized, Placebo-Controlled Trial.The Journal of pediatrics · 2019Trial
- The Role of IGF-1 and IL-10 in Childhood Stunting: Evidence From Indonesia.TheScientificWorldJournal · 2026Article
- Systemic inflammation during the neonatal period and BMI at 1 year in infants with gastroschisis: a retrospective cohort study.European journal of pediatrics · 2025Article
- Review
- Perspective: Connecting the dots between domestic livestock ownership and child linear growth in low- and middle-income countries.Maternal & child nutrition · 2024Article
- Correlation between gut microbiota composition, enteric infections and linear growth impairment: a case-control study in childhood stunting in Pidie, Aceh, Indonesia.Gut pathogens · 2023Article
- Association between asymptomatic infections and linear growth in 18-24-month-old Malawian children.Maternal & child nutrition · 2023Article
- The role of environmental enteric dysfunction in the pathogenesis of Schistosoma mansoni-associated morbidity in school-aged children.PLoS neglected tropical diseases · 2022Article
- Risk factors of stunting and wasting in Somali pre-school age children: results from the 2019 Somalia micronutrient survey.BMC public health · 2022Article
- Systemic Inflammation in the First 2 Weeks after Birth as a Determinant of Physical Growth Outcomes in Hospitalized Infants with Extremely Low Gestational Age.The Journal of pediatrics · 2022Article
- Integrating anthropometric and cardiometabolic health methods in stress, early experiences, and development (SEED) science.Developmental psychobiology · 2021Review
- Determination of modifiable risk factors for length-for-age z-scores among resource-poor Indonesian infants.PloS one · 2021Article
- DGAT1 mutations leading to delayed chronic diarrhoea: a case report.BMC medical genetics · 2020Article
- Machine learning model demonstrates stunting at birth and systemic inflammatory biomarkers as predictors of subsequent infant growth - a four-year prospective study.BMC pediatrics · 2020Article
- The Structure and Function of the Human Small Intestinal Microbiota: Current Understanding and Future Directions.Cellular and molecular gastroenterology and hepatology · 2020Review
- The association of gut microbiota characteristics in Malawian infants with growth and inflammation.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Stunting can afflict up to one-third of children in resource-constrained countries. We hypothesized that low-grade systemic inflammation (defined as elevations in serum C-reactive protein or alpha-1-acid glycoprotein) in infancy suppresses the growth hormone⁻insulin-like growth factor (IGF) axis and is associated with subsequent stunting. Blood samples of 590 children from periurban Dar es Salaam, Tanzania, were obtained at 6 weeks and 6 months of age as part of a randomized controlled trial. Primary outcomes were stunting, underweight, and wasting (defined as length-for-age, weight-for-age and weight-for-length
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Registered trials
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