ArticleJournal of neonatal-perinatal medicine2019
Natural drugs, not so natural effects: Neonatal abstinence syndrome secondary to 'kratom'.
Article in Journal of neonatal-perinatal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 41 citations in OpenAlex.
- Endogenous Opioid Activity as the Mechanism of Action for Mitragyna speciosa (Kratom): The Current State of the Evidence.Advances in neurobiology · 2024Review
- Clinical Implications of Kratom (Current addiction reports · 2023Review
- Health Effects Associated With Kratom (Substance abuse : research and treatment · 2022Review
- Psychoactive Substances of Natural Origin: Toxicological Aspects, Therapeutic Properties and Analysis in Biological Samples.Molecules (Basel, Switzerland) · 2021Review
- Case Report: Treatment of Kratom Use Disorder With a Classical Tricyclic Antidepressant.Frontiers in psychiatry · 2021Article
- Kratom-Pharmacology, Clinical Implications, and Outlook: A Comprehensive Review.Pain and therapy · 2020Review
- Can Kratom (Frontiers in psychiatry · 2020Article
- Cardiac arrest in a young healthy male patient secondary to kratom ingestion: is this 'legal high' substance more dangerous than initially thought ?BMJ case reports · 2019Article
- Review
- A reply to Henningfield, Fant & Wang (2018): regulatory action to control kratom is long overdue.Psychopharmacology · 2019Article
- Opioid Use in Pregnant Women and Neonatal Abstinence Syndrome-A Review of the Literature.Toxics · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMitragyna speciosa, also known as kratom, is obtained from the coffee plant family 'Rubiaceae.' Kratom is available in the form of capsules, whole, processed and powdered leaves, and as liquids. Secondary to its 'natural herb' status and opioid effects, it is misconceived to be a safe alternative for the treatment of chronic pain. The use of kratom has increased by tenfold in the United States since 2010. METHODS AND
resultsWe report a term neonate who was born to a chronic kratom user and required treatment with opiates for neonatal drug withdrawal.
conclusionPhysicians should be aware of these herbal supplements and its potential withdrawal effects in newborn which cannot be picked up by the standard toxicology screen.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.