← Metformin × quality of life & behaviour

SynthesisJournal of Alzheimer's disease : JAD2018

Metformin Use Associated with Reduced Risk of Dementia in Patients with Diabetes: A Systematic Review and Meta-Analysis.

Jared M Campbell et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 2018

Not counted

Probably lowered quality of life & behaviour

−45%−62% to −22%

Bigger than 8 in 10 on the map

As reported

OR 0.55, 95% CI 0.38–0.78

Not counted

Probably lowered quality of life & behaviour

−24%−61% to −12%

Bigger than 5 in 10 on the map

As reported

HR 0.76, 95% CI 0.39–0.88

Two numbers in the abstract

the abstract, start to end

… in diabetic metformin (Odds ratio = 0.55, 95% CI 0.38 to 0.78), while six studies showed that dementia incidence was also significantly reduced (Hazard ratio = 0.76, 95% CI 0.39 to 0.88).

← favours treatmentfavours comparator →
could be chance
Quality of life & behaviour
OR 0.550.38–0.78
Quality of life & behaviour
HR 0.760.39–0.88
MetforminQuality of life & behaviour
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Full record →Abstract, authors, funding and every citing paper · PMID 30149446