Evidence map›Paper›PMID 30148799›Full record

ReviewCurrent opinion in rheumatology2018

An update on autoantibodies in scleroderma.

Christopher A Mecoli, Livia Casciola-Rosen

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. IP-to-MS: An Unbiased Workflow for Antigen Profiling.Journal of proteome research · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Pathogenesis of autoimmune disease.Nature reviews. Nephrology · 2023
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Biomarkers in systemic sclerosis.Current opinion in rheumatology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christopher A MecoliDivision of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Livia Casciola-Rosen
Johns Hopkins University · US

Funding

Sample Processing and Immunoassay Research CoreP30AR070254 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI CLIFTON O BINGHAM, Antony Rosen · 2016 to 2026
$8.9M
NIAMS NIH HHS P30 AR070254
6 · The paper itself

Abstract

purpose of reviewNew research continues to provide important insights into the utility of antibody specificities. This review provides an update of recent findings, and the important insights they provide into disease mechanism. RECENT

findingsA growing number of autoantibodies have been discovered in scleroderma patients with unique clinical associations. A subgroup of these antibodies may have functional consequences and contribute to disease pathogenesis, driving the vascular and fibrotic phenotype. Recent research into the relationship between malignancy and scleroderma onset provides important new insights into disease mechanism, and highlights the utility of autoantibodies as unique research probes. SUMMARY: Continued advances in the study of scleroderma antibody specificities has led to important insights into disease pathogenesis and clinical subgrouping. These advances include newly described specificities, functional antibodies and an emerging understanding of the cancer-scleroderma relationship.

Indexed as

Immunity, InnateAutoantibodiesHumansPhenotypeScleroderma, SystemicAutoantibodies

Identifiers

PMID30148799
PMCPMC6546089
OpenAlexW2888869823

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.