ArticleMedicina oral, patologia oral y cirugia bucal2018
Clinicopathologic and immunohistochemical characterization of 14 cases of angioleiomyomas in oral cavity.
Article in Medicina oral, patologia oral y cirugia bucal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 17 citations in OpenAlex.
- Perirectal angioleiomyoma preoperatively misdiagnosed as rectal cancer: a case report.Frontiers in oncology · 2024Article
- Leiomyoma with Uncommon Localization-Incisive Papilla and Palatal Fibromucosa: A Case Report.Medicina (Kaunas, Lithuania) · 2023Article
- Leiomyoma and Leiomyosarcoma (Primary and Metastatic) of the Oral and Maxillofacial Region: A Clinicopathological and Immunohistochemical Study of 27 Cases.Head and neck pathology · 2022Article
- Epstein-Barr Virus-Associated Smooth Muscle Tumors of Larynx: A Clinicopathologic Study and Comprehensive Literature Review of 12 Cases.Head and neck pathology · 2021Review
- Multimodality Imaging Evaluation of an Uncommon Benign Nasal Cavity Tumor : Case Report on Angioleiomyoma of the Nasomaxillary Junction.Clinical neuroradiology · 2021Article
- Pediatric leiomyoma of the oral cavity: A rare entity.Journal of oral and maxillofacial pathology : JOMFP · 2021Article
- Clinical, Imaging and Histopathology of Angioleiomyoma of the Buccal Cheek.Case reports in dentistry · 2021Article
- Vascular leiomyoma in the oral cavity - Report of two cases.Journal of clinical and experimental dentistry · 2019Article
- Clinical and Immunohistochemical Features of Oral Angioleiomyoma: A Comprehensive Review of the Literature and Report of a Case in a Young Patient.Case reports in dentistry · 2019Article
- Angioleiomyoma of the Lower Lip.Annals of maxillofacial surgeryArticle
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Authors and funding
7 authors at 1 institution in 2 countries.
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Abstract
backgroundAngioleiomyoma (ALM) is a benign neoplasm that originates from vascular smooth muscle. It is extremely rare in oral cavity. The objective of this study was to evaluate the clinicopathological and immunohistochemical characteristics of all oral angioleiomyomas registered in a Center of Diagnosis of Oral Diseases from 1959 to 2017. MATERIAL AND
methodsSlides from 14 cases of ALM stained with hematoxylin and eosin (H&E) were analyzed to confirm the diagnosis. Moreover, an immunohistochemical panel with alpha-smooth muscle actin (alpha-SMA), desmin, AE1/AE3, CD68, S-100, and CD34 antibodies was performed to evaluate semi-quantitatively the positive cells.
resultsALM correspond to 0.08% of all benign oral tumors analyzed during the 57-year period. The mean age of the patients was 45 years with a predilection to males (58%). The most frequently reported site was lips (50%). Microscopic analysis on H&E sections revealed similar pattern in all cases, showing well-circumscribed and encapsulated tumors, characterized by a proliferation of smooth muscle cells and wide vascular spaces of varying sizes. The predominant immuno profiles were: alpha-smooth muscle actin (alpha-SMA) positive (strong immunoreactivity); positive variable pattern for desmin, negative immunoprofile for AE1/AE3, CD68, and S-100. The endothelial cells of vascular spaces were CD34+.
conclusionsBased on the results, the alpha-SM actin can be elected as a good marker for angioleiomyomas and can help the confirmation of the morphologic diagnosis of this lesion.
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