Evidence map›Paper›PMID 30148412›Full record

ReviewOrganogenesis2018

Application of drug delivery systems for the controlled delivery of growth factors to treat nervous system injury.

Fukai Ma, Fan Wang, Ronggang Li, Jianhong Zhu

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Organogenesis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Fukai Maa Department of Neurosurgery , Fudan University Huashan Hospital and National Key Laboratory of Medical Neurobiology, the Institutes of Brain Science, Shanghai Medical College, Fudan University , Shanghai , China.ORCID 0000-0003-0997-2626
Fan Wanga Department of Neurosurgery , Fudan University Huashan Hospital and National Key Laboratory of Medical Neurobiology, the Institutes of Brain Science, Shanghai Medical College, Fudan University , Shanghai , China.
Ronggang Lia Department of Neurosurgery , Fudan University Huashan Hospital and National Key Laboratory of Medical Neurobiology, the Institutes of Brain Science, Shanghai Medical College, Fudan University , Shanghai , China.
Jianhong Zhua Department of Neurosurgery , Fudan University Huashan Hospital and National Key Laboratory of Medical Neurobiology, the Institutes of Brain Science, Shanghai Medical College, Fudan University , Shanghai , China.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nervous system injury represent the most common injury and was unique clinical challenge. Using of growth factors (GFs) for the treatment of nervous system injury showed effectiveness in halting its process. However, simple application of GFs could not achieve high efficacy because of its rapid diffusion into body fluids and lost from the lesion site. The drug delivery systems (DDSs) construction used to deliver GFs were investigated so that they could surmount its rapid diffusion and retain at the injury site. This study summarizes commonly used DDSs for sustained release of GFs that provide neuroprotection or restoration effects for nervous system injury.

Indexed as

Drug Delivery SystemsAnimalsBiocompatible MaterialsDelayed-Action PreparationsHumansImmobilized ProteinsIntercellular Signaling Peptides and ProteinsTrauma, Nervous SystemBiocompatible MaterialsDelayed-Action PreparationsImmobilized ProteinsIntercellular Signaling Peptides and Proteinsdrug delivery systemsgrowth factorsnervous system injuryneurogenesis

Identifiers

PMID30148412
PMCPMC6300096
OpenAlexW2889157414

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.