Evidence map›Paper›PMID 30148217›Full record

ArticleClinical and translational radiation oncology2018

A prospective in silico analysis of interdisciplinary and interobserver spatial variability in post-operative target delineation of high-risk oral cavity cancers: Does physician specialty matter?

Sweet Ping Ng, Brandon A Dyer, Jayashree Kalpathy-Cramer, Abdallah Sherif Radwan Mohamed, Musaddiq J Awan, G Brandon Gunn, Jack Phan, Mark Zafereo, J Matthew Debnam, Carol M Lewis and 12 more

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Journal of medical imaging (Bellingham, Wash.) · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Deep learning-based GTV contouring modeling inter- and intra- observer variability in sarcomas.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 8 institutions in 1 country.

Sweet Ping NgDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Brandon A DyerDepartment of Radiation Oncology, UC Davis Comprehensive Cancer Center, Sacramento, California, USA.
Jayashree Kalpathy-CramerAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Abdallah Sherif Radwan MohamedDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Musaddiq J AwanDepartment of Radiation Oncology, Case Western Reserve University, Cleveland, Ohio, USA.
G Brandon GunnDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Jack PhanDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Mark ZafereoDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
J Matthew DebnamDepartment of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Carol M LewisDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Rivka R ColenDepartment of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Michael E KupfermanDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Nandita Guha-ThakurtaDepartment of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Guadalupe CanahuateDepartment of Electrical & Computer Engineering, University of Iowa, Iowa City, Iowa, USA.
G Elisabeta MaraiDepartment of Computer Science, University of Illinois at Chicago, Chicago, Illinois, USA.
David VockDepartment of Biostatistics, University of Minnesota of Public Health, Minneapolis, Minnesota, USA.
Bronwyn HamiltonDepartment of Radiology, Oregon Health & Science University, Portland, Oregon, USA.
John HollandDepartment of Radiation Oncology, Oregon Health & Science University, Portland, Oregon, USA.
Carlos E CardenasDepartment of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Stephen LaiDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
David RosenthalDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Clifton David FullerDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
The University of Texas MD Anderson Cancer Center · USOregon Health & Science University · USCase Western Reserve University · USMassachusetts General Hospital · USUC Davis Comprehensive Cancer CenterUniversity of Illinois Chicago · USUniversity of Iowa · USUniversity of Minnesota · US

Funding

SMART-ACT: Spatial Methodologic Approaches for Risk Assessment and Therapeutic Adaptation in Cancer TreatmentR01CA214825 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CANAHUATE, GUADALUPE, FULLER, CLIFTON DAVID · 2017 to 2019
$1.1M
6 · The paper itself

Abstract

backgroundThe aim of this study was to determine the interdisciplinary agreement in identifying the post-operative tumor bed.

methodsThree radiation oncologists (ROs), four surgeons, and three radiologists segmented post-operative tumor and nodal beds for three patients with oral cavity cancer. Specialty cohort composite contours were created by STAPLE algorithm implementation results for interspecialty comparison. Dice similarity coefficient and Hausdorff distance were utilized to compare spatial differentials between specialties.

resultsThere were significant differences between disciplines in target delineation. There was unacceptable variation in Dice similarity coefficient for each observer and discipline when compared to the STAPLE contours. Within surgery and radiology disciplines, there was good consistency in volumes. ROs and radiologists have similar Dice similarity coefficient scores compared to surgeons.

conclusionThere were significant interdisciplinary differences in perceptions of tissue-at-risk. Better communication and explicit description of at-risk areas between disciplines is required to ensure high-risk areas are adequately targeted.

Indexed as

InterdisciplinaryInterobserverOral cavity cancerPost-operativeTarget delineation

Identifiers

PMID30148217
PMCPMC6105928
OpenAlexW2886581694

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.