Evidence map›Paper›PMID 30148158›Full record

ArticleInternational journal of genomics2018

The Effect of Citalopram on Genome-Wide DNA Methylation of Human Cells.

Riya R Kanherkar, Bruk Getachew, Joseph Ben-Sheetrit, Sudhir Varma, Thomas Heinbockel, Yousef Tizabi, Antonei B Csoka

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Chaperone Sigma1R and Antidepressant Effect.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Riya R KanherkarEpigenetics Laboratory, Department of Anatomy, Howard University, 520 W St. NW, Washington, DC 20059, USA.
Bruk GetachewDepartment of Pharmacology, Howard University, 520 W St. NW, Washington, DC 20059, USA.
Joseph Ben-SheetritTel-Aviv Brüll Community Mental Health Center, Clalit Health Services, 9 Hatzvi St., 6719709 Tel-Aviv, Israel.
Sudhir VarmaHiThru Analytics LLC, 1001 Spring St. No. 219, Silver Spring, MD 20910, USA.
Thomas HeinbockelEpigenetics Laboratory, Department of Anatomy, Howard University, 520 W St. NW, Washington, DC 20059, USA.
Yousef TizabiDepartment of Pharmacology, Howard University, 520 W St. NW, Washington, DC 20059, USA.
Antonei B CsokaEpigenetics Laboratory, Department of Anatomy, Howard University, 520 W St. NW, Washington, DC 20059, USA.ORCID 0000-0002-7287-5856
Howard University · USClalit Health Services · IL

Funding

Advancing aging research through development of minority GerontologistsR25AG047843 · NIA · HOWARD UNIVERSITY · PI DUTTAROY, ATANU · 2014 to 2024
$3.3M
NIA NIH HHS R25 AG047843
6 · The paper itself

Abstract

Commonly used pharmaceutical drugs might alter the epigenetic state of cells, leading to varying degrees of long-term repercussions to human health. To test this hypothesis, we cultured HEK-293 cells in the presence of 50

Identifiers

PMID30148158
PMCPMC6083487
OpenAlexW2884602212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.