Evidence map›Paper›PMID 30148011›Full record

ArticleCureus2018

Prevalence of Rheumatic Diseases in a Tertiary Care Hospital of Karachi.

Zainab Mohsin, Arifa A Asghar, Arisha Faiq, Ilma Khalid, Ibtehaj Ul-Haque, Sameen Rehman, Saffia I Ahmed, Syeda Tooba Basalat, Abeeha Aimen, Shiza Shafique and 6 more

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Cureus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06888973 (Mesenchymal Stem Cells Infusion in Patients With Autoimmune Diseases - A Phase II Clinical Trial), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06888973 phase1 / phase2enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Mesenchymal Stem Cells Infusion in Patients With Autoimmune Diseases - A Phase II Clinical Trial

TypeinterventionalSponsorNational Institute of Blood and Marrow Transplant (NIBMT), PakistanRan2025 to 2026Enrolled200ConditionsRheumatoid Arthritis, Systemic Lupus Erythematosus (SLE), Systemic Sclerosis, Ankylosing Spondylitis (AS)ArmsMesenchymal Stem Cells, Placebo
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Zainab MohsinDow Medical College, Dow University of Health Sciences (DUHS), Karachi, PAK.
Arifa A AsgharDow Medical College, Dow University of Health Sciences (DUHS), Karachi, PAK.
Arisha FaiqDow Medical College, Dow University of Health Sciences (DUHS), Karachi, PAK.
Ilma KhalidDow Medical College, Dow University of Health Sciences (DUHS), Karachi, PAK.
Ibtehaj Ul-HaqueDow Medical College, Dow University of Health Sciences (DUHS), Karachi , PAK.
Sameen RehmanDow Medical College, Dow University of Health Sciences (DUHS), Karachi, PAK.
Saffia I AhmedDow Medical College, Dow University of Health Sciences (DUHS), Karachi, PAK.
Syeda Tooba BasalatDow Medical College, Dow University of Health Sciences (DUHS), Karachi, PAK.
Abeeha AimenDow Medical College, Dow University of Health Sciences (DUHS), Karachi, PAK.
Shiza ShafiqueDow University of Health Sciences, Civil Hospital, Karachi, PAK.
Ayesha HanifDow Medical College, Dow University of Health Sciences (DUHS), Karachi, Pakistan, Karachi, PAK.
Muhammad Waqas IqbalDow Medical College, Dow University of Health Sciences (DUHS), Karachi, Pakistan, Karachi, PAK.
Syed A SamadDow Medical College, Dow University of Health Sciences (DUHS), Karachi, Pakistan, Karachi, PAK.
Faiza SiddiquiDow Medical College, Dow University of Health Sciences (DUHS), Karachi, Pakistan, Karachi, PAK.
Ishaque HameedDow Medical College, Dow University of Health Sciences (DUHS), Karachi, Pakistan, Karachi, PAK.
Marzia SafriDow Medical College, Dow University of Health Sciences (DUHS), Karachi, Pakistan, Karachi, PAK.
Dow University of Health Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRheumatic diseases are referred to as conditions affecting joints, muscles, ligaments, tendons, and bones. According to a report by World Health Organization, rheumatic and musculoskeletal diseases were labeled as the second most reported cause of disability around the globe. The purpose of this study was to estimate the prevalence of rheumatic diseases in a tertiary care hospital of Karachi; additionally, associations with age groups, gender and comorbidities were obtained as well.

methodsA cross-sectional study was conducted at the Orthopedic Out Patient Department (OPD) of Dr. Ruth KM Pfau Civil Hospital, Karachi over a span of three months in 2018 (February till May). All 346 patients were follow-up diagnosed cases in the age range of 11-90 years, divided into groups of adolescents, young adults, adults, and older adults. The subjects were questioned about their symptoms, duration of illness, presence of comorbidities, genetic background and the therapy they are undergoing along with compliance. Simple statistical analysis of frequency was done, whereas chi-square test was applied to study associations with gender, age groups, and comorbidities.

resultsDuring the study period, a total of 2000 patients visited the orthopedic OPD, 346 of which were diagnosed cases of rheumatic diseases, yielding a prevalence of 17.3%. The mean age of rheumatic patients who partook in the study was 46.15 ± 15.49 (Range: 12 - 84). Osteoarthritis was recorded as the most prevalent condition, followed by non-specific low back pain and rheumatoid arthritis. Osteoarthritis was statistically significant in young adults, adults, and older adults, while non-specific low back pain had significant associations with gender, young adults, and adults. Diabetes was significantly associated with osteoarthritis, non-specific low back pain, shoulder pain syndrome and psoriatic arthritis, while hypertension significantly co-existed with systemic lupus erthematosus.

conclusionRheumatic diseases constitute a major disease burden in almost all of the age groups, especially in young patients (18-40 years) within our setup.

Indexed as

musculoskeletal disordersnon-specific low back painosteoarthritisrheumatic diseaserheumatoid arthritistertiary care hospital

Identifiers

PMID30148011
PMCPMC6107035
OpenAlexW2809549177

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.