ArticleCase reports in ophthalmological medicine2018
Topical Treatment with Cord Blood Serum in Glaucoma Patients: A Preliminary Report.
Article in Case reports in ophthalmological medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Cord Blood Serum (CBS)-Based Eye Drops Modulate Light-Induced Neurodegeneration in Albino Rat Retinas.Biomolecules · 2020Trial
- Safety and exploratory functional effects of topical cord blood serum in glaucoma patients.Scientific reports · 2026Article
- Multi-component cord blood banking: a proof-of-concept international exercise.Blood transfusion = Trasfusione del sangue · 2023Article
- Allogeneic Umbilical Cord Plasma Eyedrops for the Treatment of Recalcitrant Dry Eye Disease Patients.Journal of clinical medicine · 2023Article
- Impact of Freeze-Drying on Cord Blood (CB), Serum (S), and Platelet-Rich Plasma (CB-PRP) Preparations on Growth Factor Content and In Vitro Cell Wound Healing.International journal of molecular sciences · 2022Article
- Impact of blood source and component manufacturing on neurotrophin content and in vitro cell wound healing.Blood transfusion = Trasfusione del sangue · 2022Article
- Recycling Apparent Waste Into Biologicals: The Case of Umbilical Cord Blood in Italy and Spain.Frontiers in cell and developmental biology · 2021Article
- Umbilical Cord Blood and Serum for the Treatment of Ocular Diseases: A Comprehensive Review.Ophthalmology and therapy · 2020Review
- Effects of Cord Blood Serum (CBS) on viability of retinal Müller glial cells under in vitro injury.PloS one · 2020Article
- Regenerative Therapy Using Umbilical Cord Serum.In vivo (Athens, Greece)Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo report data which happened to be observed in two glaucoma patients treated with Cord Blood Serum (CBS) eye drops.
designA case report and retrospective data analysis.
methodsCBS topical eye drops, characterized in advance for growth factors (GFs) content, were administered for two months with the aim to relieve their subjective symptoms, in two patients who had referred ocular surface discomfort, although in absence of any sign of keratopathy. As patients were also affected by advanced glaucoma at risk of vision loss and under treatment with hypotensive drugs, they had been also monitored over the same period with IOP controls and visual field tests in our unit.
resultsDuring subsequent visits, data from Mean Deviation and Pattern Standard Deviation in the visual fields were retrospectively collected and compared with before and after treatment with CBS, and an amelioration was observed.
conclusionsCBS contains a combination of GFs, which potentially exert a neuroprotective action and elect CBS as an interesting natural source to be delivered in neurodegenerative ocular disorders. The incidentally observed amelioration in these two patients deserves further investigation in this respect.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.