Evidence map›Paper›PMID 30147847›Full record

ArticleWorld journal of gastrointestinal oncology2018

Pancreatic, periampullary and biliary cancer with liver metastases: Should we consider resection in selected cases?

Rachael Chang Lee, Harsh Kanhere, Markus Trochsler, Vy Broadbridge, Guy Maddern, Timothy J Price

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. [Preoperative diagnostics in periampullary adenocarcinomas].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Rachael Chang LeeDepartment of Medical Oncology, the Queen Elizabeth Hospital, Adelaide 5011, Australia.
Harsh KanhereDepartment of Surgery, the Queen Elizabeth Hospital, Adelaide 5011, Australia.
Markus TrochslerDepartment of Surgery, the Queen Elizabeth Hospital, Adelaide 5011, Australia.
Vy BroadbridgeDepartment of Medical Oncology, the Queen Elizabeth Hospital, Adelaide 5011, Australia.
Guy MaddernDepartment of Surgery, the Queen Elizabeth Hospital, Adelaide 5011, Australia.
Timothy J PriceDepartment of Medical Oncology, the Queen Elizabeth Hospital, Adelaide 5011, Australia.
University of Adelaide · AUQueen Elizabeth Hospital · AUCreative Research Enterprises (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo analyse the safety and efficacy of curative intent surgery in biliary and pancreatic cancer.

methodsAn extensive literature review was performed using MEDLINE, Google Scholar and EMBASE to identify articles regarding hepato-pancreatoduodenectomy or resection of liver metastasis in patients with pancreatic, biliary tract, periampullary and gallbladder cancers.

resultsA total of 19 studies were identified and reviewed. Major hepatectomy was undertaken in 391 patients. The median overall survival for pancreatic cancer ranged from 5-36 mo and for biliary tract/gallbladder cancer, it was 8-38 mo. The 30 d mortality rate was only 1%-9%. Overall Survival was significantly better for patients, who had good response to neoadjuvant chemotherapy, underwent metachronous liver resection and who had intestinal type tumours.

conclusionResection of liver metastases in pancreatic and biliary cancers may provide survival benefit without compromising safety and quality of life in a very select group of patients. These data may be utilised to formulate selection criteria that may allow future investigation of resection in the era of more effective systemic therapy.

Indexed as

CholangiocarcinomaGall bladderLiver resectionPancreasReview

Identifiers

PMID30147847
PMCPMC6107475
OpenAlexW2886717944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.