Evidence map›Paper›PMID 30147646›Full record

ArticleFrontiers in neuroanatomy2018

Clinical Phenotypes Associated to Engrailed 2 Gene Alterations in a Series of Neuropediatric Patients.

Francisco Carratala-Marco, Patricia Andreo-Lillo, Marta Martinez-Morga, Teresa Escamez-Martínez, Arancha Botella-López, Carlos Bueno, Salvador Martinez

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Functional Outcomes of Cerebellar Malformations.Frontiers in cellular neuroscience · 2019
    Review
  6. Biomarkers in schizophrenia - past, present and future.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Francisco Carratala-MarcoNeuropaediatric Unit, University Hospital of San Juan de Alicante, Elche, Spain.
Patricia Andreo-LilloNeuropaediatric Unit, University Hospital of San Juan de Alicante, Elche, Spain.
Marta Martinez-MorgaNeuroscience Institute UMH-CSIC, CIBERSAM-ISCIII, Alicante, Spain.
Teresa Escamez-MartínezIMIB-Arrixaca, University of Murcia, Murcia, Spain.
Arancha Botella-LópezNeuroscience Institute UMH-CSIC, CIBERSAM-ISCIII, Alicante, Spain.
Carlos BuenoNeuroscience Institute UMH-CSIC, CIBERSAM-ISCIII, Alicante, Spain.
Salvador MartinezNeuroscience Institute UMH-CSIC, CIBERSAM-ISCIII, Alicante, Spain.
Centro de Investigación Biomédica en Red de Salud Mental · ESHospital Universitari Sant Joan D'Alacant · ESInstituto de Neurociencias · ESInstituto de Salud Carlos III · ESUniversidad de Murcia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The engrailed homeobox protein (EN) plays an important role in the regionalization of the neural tube. EN distribution regulates the cerebellum and midbrain morphogenesis, as well as retinotectal synaptogenesis. In humans, the

Indexed as

behavioral disorderscerebral palsyEN2encephalic structural anomaliesengrailed 2epilepsygenotype-genotype correlationmental retardation

Identifiers

PMID30147646
PMCPMC6095973
OpenAlexW2887068386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.