Evidence map›Paper›PMID 30147337›Full record

ArticleOncoTargets and therapy2018

Prognostic value of nutritional markers in nasopharyngeal carcinoma patients receiving intensity-modulated radiotherapy: a propensity score matching study.

Ronald Wihal Oei, Lulu Ye, Juan Huang, Fangfang Kong, Tingting Xu, Chunying Shen, Xiaoshen Wang, Xiayun He, Lin Kong, Chaosu Hu and 1 more

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Impact of weight loss on treatment interruption and unplanned hospital admission in head and neck cancer patients undergoing curative (chemo)-radiotherapy in Hong Kong.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
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  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Ronald Wihal OeiDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, People's Republic of China, dryinghongmei@163.com.
Lulu YeDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, People's Republic of China, dryinghongmei@163.com.
Juan HuangDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, People's Republic of China, dryinghongmei@163.com.
Fangfang KongDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, People's Republic of China, dryinghongmei@163.com.
Tingting XuDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, People's Republic of China, dryinghongmei@163.com.
Chunying ShenDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, People's Republic of China, dryinghongmei@163.com.
Xiaoshen WangDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, People's Republic of China, dryinghongmei@163.com.
Xiayun HeDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, People's Republic of China, dryinghongmei@163.com.
Lin KongDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, People's Republic of China, dryinghongmei@163.com.
Chaosu HuDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, People's Republic of China, dryinghongmei@163.com.
Hongmei YingDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, People's Republic of China, dryinghongmei@163.com.
Shanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the prognostic value of nutritional markers for survival in nasopharyngeal carcinoma (NPC) patients receiving intensity-modulated radiotherapy (IMRT), with or without chemotherapy. PATIENTS AND

methodsThis retrospective study included 412 NPC patients who received IMRT-based treatment. Weight loss (WL) during treatment, hemoglobin level (Hb) and serum albumin level (Alb) before treatment were measured. The prognostic values of these markers for overall survival (OS), locoregional recurrence-free survival (LRFS) and distant metastasis-free survival (DMFS) were analyzed using Kaplan-Meier method and Cox proportional hazards regression analysis. Propensity score matching was performed to reduce the effect of confounders.

resultsWL, Hb and Alb were significantly correlated with each other and inflammatory markers. Adjusted Cox regression analysis showed that critical weight loss (CWL) (WL≥5%) was an independent prognostic factor for OS (HR: 2.399, 95% CI: 1.267-4.540,

conclusionCWL, Hb and Alb have a significant impact on survival in NPC patients undergoing IMRT. They can be utilized in combination with conventional staging system to predict the prognosis of NPC patients treated with IMRT.

Indexed as

albuminhemoglobinintensity-modulated radiotherapynasopharyngeal carcinomasurvivalweight loss

Identifiers

PMID30147337
PMCPMC6098427
OpenAlexW2885192790

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.