Evidence map›Paper›PMID 30147136›Full record

ArticleHospital pharmacy2018

Intravenous Push Administration of Antibiotics: Literature and Considerations.

Samantha Spencer, Heather Ipema, Patricia Hartke, Courtney Krueger, Ryan Rodriguez, Alan E Gross, Michael Gabay

Abstract read
In one paragraph

Article in Hospital pharmacy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Therapeutic Interventions forJournal of clinical medicine · 2024
    Review
  3. Article
  4. Phenobarbital Dosing for the Treatment of Alcohol Withdrawal Syndrome: A Review of the Literature.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2024
    Review
  5. Parenteral medication use in hospital at home: Challenges and opportunities.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samantha SpencerCollege of Pharmacy, University of Illinois at Chicago, USA.ORCID https://orcid.org/0000-0002-8496-3554
Heather IpemaCollege of Pharmacy, University of Illinois at Chicago, USA.ORCID https://orcid.org/0000-0002-0981-1358
Patricia HartkeCollege of Pharmacy, University of Illinois at Chicago, USA.
Courtney KruegerCollege of Pharmacy, University of Illinois at Chicago, USA.
Ryan RodriguezCollege of Pharmacy, University of Illinois at Chicago, USA.
Alan E GrossCollege of Pharmacy, University of Illinois at Chicago, USA.
Michael GabayCollege of Pharmacy, University of Illinois at Chicago, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravenous (IV) push administration can provide clinical and practical advantages over longer IV infusions in multiple clinical scenarios, including in the emergency department, in fluid-restricted patients, and when supplies of diluents are limited. In these settings, conversion to IV push administration may provide a solution. This review compiles available data on IV push administration of antibiotics in adults, including preparation, stability, and administration instructions. Prescribing information, multiple tertiary drug resources, and primary literature were consulted to compile relevant data. Several antibiotics are Food and Drug Administration-approved for IV push administration, including many beta-lactams. In addition, cefepime, ceftriaxone, ertapenem, gentamicin, and tobramycin have primary literature data to support IV push administration. While amikacin, ciprofloxacin, imipenem/cilastatin, and metronidazole have limited primary literature data on IV push administration, available data do not support that route. In addition, a discussion on practical considerations, such as IV push best practices and pharmacodynamic considerations, is provided.

Indexed as

anti-infectivesdrug stabilityintravenous therapy

Identifiers

PMID30147136
PMCPMC6102793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.