Evidence map›Paper›PMID 30146972›Full record

ArticleGlobal public health2019

Are treatment supporters relevant in long-term Antiretroviral Therapy (ART) adherence? Experiences from a long-term ART cohort in Uganda.

Sarah Nakamanya, Billy N Mayanja, Richard Muhumuza, Dominic Bukenya, Janet Seeley

Open access · hybridAbstract read
In one paragraph

Article in Global public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  5. Virtual nurse support to enhance antipsychotic adherence in schizophrenia: A South African perspective.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sarah Nakamanyaa MRC/UVRI and LSHTM Uganda Research Unit , Entebbe , Uganda.
Billy N Mayanjaa MRC/UVRI and LSHTM Uganda Research Unit , Entebbe , Uganda.
Richard Muhumuzaa MRC/UVRI and LSHTM Uganda Research Unit , Entebbe , Uganda.
Dominic Bukenyaa MRC/UVRI and LSHTM Uganda Research Unit , Entebbe , Uganda.
Janet Seeleya MRC/UVRI and LSHTM Uganda Research Unit , Entebbe , Uganda.
Uganda Virus Research Institute · UGLondon School of Hygiene & Tropical Medicine · GB

Funding

Medical Research Council MC_U950080928
6 · The paper itself

Abstract

backgroundThis study aimed to understand the relevance of treatment supporters in adherence among people living with HIV taking Anti-retroviral therapy (ART) for more than five years in Uganda.

methodsIn-depth interviews were conducted with 50 participants (28 women and 22 men) of the Complications of Long-Term ART (CoLTART) cohort with experience of at least five years on ART in Uganda. Participants were stratified by line of ART regimen and viral loads of less or above 1000 copies/ml. Data were analyzed thematically.

resultsMany participants felt that a treatment supporter was most useful at the beginning of therapy before individuals get used to the drugs or when they are still weak. However, this did not reflect treatment outcomes, as many individuals without treatment supporters had failed on first line ART regimens and were switched to second line ART. Those who were still on first line had viral loads of ≥1000 copies/ml. There was a preference for female treatment supporters, many of who were persistent in their supportive role.

conclusionTreatment supporters remain important in adherence to long-term ART. HIV-care providers need to encourage the involvement of a treatment supporter for individuals taking ART long-term.

Indexed as

Medication AdherenceSocial SupportAdultAnti-Retroviral AgentsCross-Sectional StudiesFemaleHIV InfectionsHumansInterviews as TopicMaleQualitative ResearchUgandaViral LoadAnti-Retroviral AgentsART adherencelong-term ARTTreatment supportersUgandaviral load

Identifiers

PMID30146972
PMCPMC6334778
OpenAlexW2889082996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.